Brown tumors mimicking bone and lung metastases: Key role of radionuclide imaging

Charfi, Hela; Nouira, M.; Ezzairi, Faten; Sfar, R.; Guezguez, M.; Essabbah, H.

doi:10.1016/j.lpm.2015.04.021

Cited by 3 publications

(3 citation statements)

References 15 publications

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“…The main pathogenic mechanism leading to corresponds to trabecular resorption phenomena complicated by micro fractures with intra-lacunar bleeding. These are very vascular lesions which may contain necrotic centers and hemosiderin deposits, hence the characteristic brown color [4]. The reported prevalence of brown tumors has decreased to <0.1%.…”

Section: Discussionmentioning

confidence: 99%

Incidental Diagnosis of a Brown Tumor Mimicking Bone and Lung Metastasis during a Parathyroid Scintigraphy

Fokoue¹,

Mselmi²,

Abaouz³

et al. 2020

AMI

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We report herein a case of a 40-year-old male patient with chronic renal failure presenting a severe hyperparathyroidism with an elevation of parathormone level evaluated in nuclear medicine department for MIBI-Technetium-99m parathyroid scintigraphy. The parathyroid scintigraphy revealed the appearance of a preferential fixation of the MIBI-99mTc opposite the lower left pole of the thyroid and opposite the upper part of the right hemi thorax. A subsequent single-photon emission computed tomography-computed tomography focused on the cervico-thoracic region was performed and showed an ectopic parathyroid adenoma associated with an incidental brown tumor mimicking bone and lung metastases. Our case report confirms the usefulness of additional hybrid SPECT-CT imaging in the management of hyperparathyroidism.

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Section: Discussionmentioning

confidence: 99%

Incidental Diagnosis of a Brown Tumor Mimicking Bone and Lung Metastasis during a Parathyroid Scintigraphy

Fokoue¹,

Mselmi²,

Abaouz³

et al. 2020

AMI

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“…Brown tumor should be kept in mind during daily practice. This tumor is a complication of hyperparathyroidism and it may be, however, the only witness to parathyroid's hyper function [5]. That's why the clinician must think about it with patients suffering from bone pains, even when calcium is not really high, and should at least dose the PTH in serum.…”

Section: Discussionmentioning

confidence: 99%

Untitled

2017

EMIJ

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Introduction: Primary hyperparathyroidism is a common disease especially in women but rarely discovered by multiple brown tumors with near normal serum calcium.Case report: A 64-year-old man presented with disseminated bone pain. He had X-rays and a CT scan that objectified lytic lesions. These lesions correspond to multiple areas of intense uptake in bone scan evoking brown tumors. Biology showed calcium at 2.66mmol/l and PTH in serum at 2003µg/l. The diagnosis of parathyroid adenoma was highly suspected that's why we did a Tc99m sestamibi dabble phase parathyroid scan. It showed a left inferior parathyroid adenoma. Conclusion:The scintigraphic imaging is a valuable contribution to the diagnosis of brown tumor, it also allows for the etiologic diagnosis by detecting the nodule parathyroid.

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“…This tumor is a complication of hyperparathyroidism and it may be, however, the only witness to parathyroid's hyper function. 5 That's why the clinician must think about it with patients suffering from bone pains, even when calcium is not really high, and should at least dose the PTH in serum.…”

Section: Discussionmentioning

confidence: 99%

Disseminated Bone Pain Related to Brown Tumors Revealing a Parathyroid Adenoma: A Case Report

Yeddes¹

2016

EMIJ

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Introduction: Primary hyperparathyroidism is a common disease especially in women but rarely discovered by multiple brown tumors with near normal serum calcium.Case report: A 64-year-old man presented with disseminated bone pain. He had X-rays and a CT scan that objectified lytic lesions. These lesions correspond to multiple areas of intense uptake in bone scan evoking brown tumors. Biology showed calcium at 2.66mmol/l and PTH in serum at 2003µg/l. The diagnosis of parathyroid adenoma was highly suspected that's why we did a Tc 99m sestamibi dabble phase parathyroid scan. It showed a left inferior parathyroid adenoma. Conclusion:The scintigraphic imaging is a valuable contribution to the diagnosis of brown tumor, it also allows for the etiologic diagnosis by detecting the nodule parathyroid.

show abstract

Brown tumors mimicking bone and lung metastases: Key role of radionuclide imaging

Cited by 3 publications

References 15 publications

Incidental Diagnosis of a Brown Tumor Mimicking Bone and Lung Metastasis during a Parathyroid Scintigraphy

Incidental Diagnosis of a Brown Tumor Mimicking Bone and Lung Metastasis during a Parathyroid Scintigraphy

Untitled

Disseminated Bone Pain Related to Brown Tumors Revealing a Parathyroid Adenoma: A Case Report

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