Brown Tumors: The Hidden Face of Primary and Renal Hyperparathyroidism Amid Real-Life Settings
Mara Carsote,
Mihai-Lucian Ciobica,
Oana-Claudia Sima
et al.
Abstract:Brown tumors, an exceptional bone complication of severe primary (PHP) or renal (secondary) hyperparathyroidism (RHP), are caused by long-standing, elevated parathormone (PTH)-induced osteoclast activation causing multinucleated giant cell conglomerates with hemosiderin deposits in addition to the local production of cytokines and growth factors. We aim to present an adult case series including two females displaying this complication as part of a multidisciplinary complex panel in high PTH-related ailments. T… Show more
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