Brucellosis in China: history, progress and challenge

Abstract

Brucellosis is a neglected zoonosis. It causes acute febrile illness and a potentially debilitating chronic infection in humans, and livestock infection has substantial socioeconomic impact. Over the past two decades, improvements have been made to better understand the various aspects of human and animal brucellosis. Meanwhile, especially in the developing world, immense challenges that remain in controlling and eradicating brucellosis are novel diagnostics tools and efficacious vaccines. Here, we will focus on the remarkable issues on epidemiological survey, as well as the priority and challenge of brucellosis in China. Brucellosis will be controlled with meaningful collaboration between local and public partnerships effectively applying a One Health framework.

Safety and Transcriptome Analysis of Live Attenuated Brucella Vaccine Strain S2 on Non-pregnant Cynomolgus Monkeys Without Abortive Effect on Pregnant Cynomolgus Monkeys

“…Meanwhile, the authors inferred that humans probably get infected along with different kinds of animal species, among which the sheep and goats were likely at the highest risks (24). The aforementioned studies, as well as the ligatures, e.g., a recent report from our collaborators (25), consistently demonstrated the significance of the One Health concept and recommended implementing it to disrupt the Brucella transmission chain between animals and humans, as well as to strengthen the close collaboration between the local and public partnerships.…”

Editorial: Pathogenomics of the Genus Brucella and Beyond

“…In the topic MLVA was also applied in local situations to explore transmission pathways. Brucellosis is a serious public health problem in China (Jiang et al, 2020 ). Liu et al characterized isolates of B. melitensis from Ulanqab using MLVA to suggest lack of control of animal movements or movement of contaminated food products between regions.…”

Brucellosis Taking Over Covid: An Emerging New Pandemic

“…Brucellosis is not a new disease and is endemic in many countries in Asia including China, India, Indonesia and Thailand, and also in South America, the Mediterranean and the Middle East [13]. According to the World Health Organization (WHO) factsheet, although approximately 500 000 brucellosis cases are reported annually, the true incidence is always much higher than the reported number of cases [15]. Eventhough, it is not a new disease, its incidence is high, especially in parts of Asia and there is no vaccine has been developed for the disease yet.…”