Brucellosis in India — a review

Mantur, BG; Amarnath, S.

doi:10.1007/s12038-008-0072-1

Cited by 171 publications

(151 citation statements)

References 43 publications

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“…Family history of brucellosis was reported in 9% to 51% of patients (15,24,46,48). Family screening leads to early diagnosis of the disease, which may prevent complications (49,50).…”

Section: Discussionmentioning

confidence: 99%

Human Brucellosis in Macedonia – 10 Years of Clinical Experience in Endemic Region

Bosilkovski¹,

Krteva²,

Dimzova³

et al. 2010

Croat Med J

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Aim To present our 10-year clinical experience with brucellosis patients at the University Clinic for Infectious Diseases and Febrile Conditions in Skopje, Republic of Macedonia.Methods A total of 550 patients with brucellosis treated between 1998 and 2007 were retrospectively assessed for their demographic, epidemiological, and clinical characteristics and outcomes.Results Of the 550 patients, 395 (72%) were male. The median age was 34.5 years (range, 1-82). Direct contact with infected animals was recorded in 333 (61%) patients and positive family history in 310 (56%). The most frequently seen symptoms were arthralgia (438, 80%), fever (419, 76%), and sweating (394, 72%). The most common signs were fever and hepatomegaly, which were verified in 357 (65%) and 273 (50%) patients, respectively. Focal brucellosis was found in 362 patients (66%) and osteoarticular in 299 (54%). Therapeutic failures were registered in 37 (6.7%) patients. Of the 453 (82%) patients who completed a follow-up period of at least 6 months, relapses occurred in 60 (13%). ConclusionDue to non-specific clinical manifestation and laboratory parameters, brucellosis should be considered one of the differential diagnoses of any patient suffering from obscure involvement of various organs in a brucellosis-endemic region. High percentage of relapses and therapeutic failures in spite of the use of currently recommended therapeutic regimens indicates the seriousness of this zoonosis and the need to control it.

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“…Family history of brucellosis was reported in 9% to 51% of patients (15,24,46,48). Family screening leads to early diagnosis of the disease, which may prevent complications (49,50).…”

Section: Discussionmentioning

confidence: 99%

Human Brucellosis in Macedonia – 10 Years of Clinical Experience in Endemic Region

Bosilkovski¹,

Krteva²,

Dimzova³

et al. 2010

Croat Med J

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“…A large proportion of dog owners used bare hands when handling dogs with no protective clothing such as coverall, laboratory coats, boots, hand gloves, or hand washing after handling of dogs. This is risky as Brucellae can enter through intact skin and abrasions (Mantur and Amarnath, 2008).…”

Section: Discussionmentioning

confidence: 99%

Risk factors and level of awareness of canine brucellosis in Jos, Plateau state, Nigeria

Habiba¹,

Gabriel²,

Ajogi³

et al. 2015

J. Vet. Med. Anim. Health

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Jos has a large population of dogs because of its cultural acceptance as meat, good weather condition for exotic breeds, persistent security challenges and dog breeding activities which is very lucrative. This study was undertaken to determine the risk factors and level of awareness of canine brucellosis among dog owners in Jos by means of a structured questionnaire. Three hundred and fifty respondents were interviewed and 350 sera samples collected from dogs presented by these respondents were analysed using the Rose Bengal plate test (RBPT). The seropositivity of 113 (32.3%) obtained by the RBPT was compared with information provided by the respondents. Seropositivity of dogs managed indoors was 13.9% whereas it was 37.1% in those managed outdoors. A large proportion of 76.9% of the respondents lacked knowledge of canine brucellosis. Likewise, 81.4% of the respondents took no precaution before and after dog handling and a large proportion of 74.6% consumed undercooked dog meat. This study showed that there is a high risk of exposure of dog owners, handlers and Veterinarians to the disease and therefore enlightenment programmes on canine brucellosis as a zoonosis should be carried out in Jos.

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“…It is aerobic, partially acid fast and has short rods [11]. It is localized predominantly to organs with numerous macrophages such as lungs, liver, spleen, bone marrow and synovium [7].…”

Section: Microbiological Aspectsmentioning

confidence: 99%