Brucellosis in pregnancy: clinical aspects and obstetric outcomes

Vilchez, Gustavo; Espinoza, Miguel; D’Onadio, Guery; Saona, Pedro; Gotuzzo, Eduardo

doi:10.1016/j.ijid.2015.06.027

Cited by 51 publications

(84 citation statements)

References 22 publications

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“…It is important to remember that Brucella can be transmitted by breast-feeding, thus exposed/infected mothers should take caution with their newborns. Neonatal Brucella infection is associated with bacteremia and acute diseases associated with organ dysfunction and respiratory distress 16,17 . Cutaneous lesions have been reported in patients with Brucella infection, as nodules, papules, erythema, and petechial.…”

Section: Clinical Findingsmentioning

confidence: 99%

Guidelines for the management of human brucellosis in the State of Paraná, Brazil

Tuon

Cerchiari

Cequinel

et al. 2017

Rev. Soc. Bras. Med. Trop.

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Section: Clinical Findingsmentioning

confidence: 99%

Guidelines for the management of human brucellosis in the State of Paraná, Brazil

Tuon

Cerchiari

Cequinel

et al. 2017

Rev. Soc. Bras. Med. Trop.

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“…Pappas et al [11] and Gustavo et al [4] found more sacro-ileitis in the subacute phase. Genital and urinary complications come second [4]. In addition, hematological disorders have been described in pregnant women, mainly anemia [9,10,11].…”

Section: Observationmentioning

confidence: 94%

“…According to Elshamy the incidence of this infection in pregnant Saudi women extends to 12.2% [1]. A new study published in 2015 by Gustavo et al found an average of 2.3 cases per year [4].…”

Section: Observationmentioning

confidence: 99%

“…The first report on this subject dates from 1906 by Devoir [4] and the first series of brucellosis during pregnancy was published in 1938 by Del Vecchio (59 cases). In 1990, Sherif estimated the incidence of brucellosis at 3.5% of Egyptian pregnant women [5].…”

Section: Observationmentioning

confidence: 99%

“…Indeed, as for non-pregnant women, the most common medical complication is bone and joint disease [10]. Pappas et al [11] and Gustavo et al [4] found more sacro-ileitis in the subacute phase. Genital and urinary complications come second [4].…”

Section: Observationmentioning

confidence: 99%

See 2 more Smart Citations

Specificity of Brucellosis In Pregnancy: Presentation of Two Cases and Review of Literature

Fatnassi¹,

Marwen²,

Benltaifa³

et al. 2016

J Infect Dis Ther

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In pregnant women, brucellosis may have different clinical aspects, but there are no specific signs of the disease and in all cases the maternal and fetal prognosis may be involved. We report two cases of brucellosis-infected pregnant women. In the first, the diagnosis and the treatment were early and the evolution was favorable with term delivery of a healthy newborn. In the second the pregnancy was complicated by a premature delivery at 32 weeks of gestation.On the occasion of these two observations, we made a literature review to clarify the clinical features of this infection during pregnancy as well as its therapy specificities.

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Type IV Effector Secretion and Subversion of Host Functions by Bartonella and Brucella Species

Dehio

Tsolis

2017

Current Topics in Microbiology and Immunology

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Bartonella and Brucella species comprise closely related genera of the order Rhizobiales within the class α-proteobacteria. Both groups of bacteria are mammalian pathogens with a facultative intracellular lifestyle and are capable of causing chronic infections, but members of each genus have evolved broadly different infection and transmission strategies. While Brucella spp. transmit in general via the reproductive tract in their natural hosts, the Bartonella spp. have evolved to transmit via arthropod vectors. However, a shared feature of both groups of pathogens is their reliance on type IV secretion systems (T4SSs) to interact with cells in their mammalian hosts. The genomes of Bartonella spp. encode three types of T4SS, Trw, Vbh/TraG, and VirB/VirD4, whereas those of Brucella spp. uniformly contain a single T4SS of the VirB type. The VirB systems of Bartonella and Brucella are associated with distinct groups of effector proteins that collectively mediate interactions with host cells. This chapter discusses recent findings on the role of T4SS in the biology of Bartonella spp. and Brucella spp. with emphasis on effector repertoires, on recent advances in our understanding of their evolution, how individual effectors function at the molecular level, and on the consequences of these interactions for cellular and immune responses in the host.

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Brucellosis in pregnancy: clinical aspects and obstetric outcomes

Cited by 51 publications

References 22 publications

Guidelines for the management of human brucellosis in the State of Paraná, Brazil

Guidelines for the management of human brucellosis in the State of Paraná, Brazil

Specificity of Brucellosis In Pregnancy: Presentation of Two Cases and Review of Literature

Type IV Effector Secretion and Subversion of Host Functions by Bartonella and Brucella Species

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