Brucellosis is a zoonotic infection that poses a threat to both human and animal health. The aim of this study is to investigate the publication trends in research on canine brucellosis and to determine the changes and general characteristics of the disease throughout history using bibliometric analysis. For this reason, we conducted a bibliometric analysis of 316 articles published in the Scopus and Web of Science (WoS) databases from 1980 to 2022. The analysis was performed using the RStudio-Bibliometrix package and the Biblioshiny application. The publications included contributions from a total of 1241 authors. In addition, a total of 804 keywords plus and 398 author keywords were identified. The earliest study among the top 10 most cited articles dates back to 1985, while the most recent one was published in 2011. The majority of the publications were published in the years 2012 (n=17) and 2014 (n=17). The United States of America (USA) (n=55), Brazil (n=40), and Argentina (n=25) were identified as the countries with the highest number of published articles. Notably, Switzerland ranked first in terms of the average number of citations per article category (n=55.50), despite only two publications being attributed to this country. Keid L. (n=15), Lucero N. (n=14), Carmichael L. (n=13), and Kim J. (n=13) emerged as the most prolific contributors. Lucero N. obtained the highest number of total citations (TC=408). In the initial years of publication, the disease was predominantly characterized by keywords such as "brucellosis," "infection," "abortus," and "Brucella canis". However, keywords related to diagnosis and treatment, such as "diagnosis," "serodiagnosis," "vaccine," and "agar gel," gained significance and became increasingly relevant. The themes and sub-themes identified through this study can provide a basis for further investigation and scientific inquiry, thus contributing to the development of new research questions and opportunities for future studies.