Bruxism Influence on Volume and Interleukin-1β Concentration of Gingival Crevicular Fluid: A Preliminary Study

Abstract

Bruxism is occlusal behaviour that often leads to stomatognathic system overload. Inflammatory markers in the periodontium are detectable in the gingival crevicular fluid (GCF). GCF production fluctuates due to various factors. Our study aimed to assess the effect of tooth clenching or grinding on GCF volume and proinflammatory IL-1β concentration in GCF. This pilot study was carried out on 20 participants aged 21 to 28 with good general health (per 10 people studied and control groups). GCF volume was measured with Periotron 8010 after absorbing for 30 s with PerioPaper strips. Twelve samples were collected from each patient—the buccal and lingual surfaces of teeth 16, 11, 24, 36, 31, and 44 were included. Laboratory examination of IL-1β concentration was performed. In patients with pathological tooth wear, a tendency to increase GCF secretion and IL-1β concentration in GCF was found. GCF volumes were higher in posterior teeth, while IL-1β levels were higher in anterior teeth. Crevices at the molars seem to have a potential predictive value in diagnosing periodontal microinflammation in patients with probable bruxism. Due to occlusal overload, these bruxists are more prone to microinflammatory processes in the periodontium. Further studies in a broader group are required to confirm this correlation.

Neopterin Levels in Periodontitis and after Nonsurgical Periodontal Therapy: Evaluation of Gingival Crevicular Fluid, Oral Fluid, Serum and Urinary Samples—A Case-Control Study

“…GCF is a transudate or exudate of human plasma and depends on vascular permeability, which increases with the inflammation of the periodontal tissue [ 40 , 41 ]. Secreted in site of inflammation gives the best information about the ongoing inflammatory condition [ 40 , 42 , 43 ]. In our study, the evaluation of Np concentrations and TA revealed different results.…”

Common therapeutic approaches in sleep and awake bruxism — an overview

“…Bodily functions disturbed by bruxism can include, among other things, increased activity of the masticatory muscles, masticatory muscle hypertrophy (especially of the masseter), scalloped or burning tongue, linea alba on the cheeks along the bite line, tooth tissue damage (enamel cracks, abfractions, excessive tooth wear beyond what is expected with age) [9,21,22], repeated damage to prosthetic restorations, disturbances of the amount and composition of secreted saliva, an often severe manifestation of craniofacial pain, stiffness of the TMJ [23,24], gingival fluid secretion increase [25], bone exostoses, and periodontal leases (increased tooth mobility, gingival recessions) [21-23, 26, 27].…”

“…Due to the variety of symptoms and the overlaps with other conditions, a bruxism diagnosis requires careful evaluation that includes questionnaires, records of past bruxism episodes, and thorough examination. To confirm the diagnosis of bruxism, there are two different methods: a non-instrumental method based on the patient's description of symptoms, questionnaires, medical history, and clinical examinations [21,25,[42][43][44]; and an instrumental method using electromyography (EMG) and polysomnography, showing muscle activity during sleep and the lack of associated epileptic activity [1].…”

Evaluation of gingival crevicular fluid volume with periopapers in patients who have recovered from COVID-19 infections

“…The GCF volume (GCFV) is proportional to the severity of periodontal inflammation, and the release and components of GCF provide significant information about periodontal disease development (10). GCFV can also change in conditions such as smoking (11), bruxism (12), diabetes, and periodontal disease (13).…”