Bryophyllum pinnatum and Related Species Used in Anthroposophic Medicine: Constituents, Pharmacological Activities, and Clinical Efficacy

Abstract

ReviewsThis document was downloaded for personal use only. Unauthorized distribution is strictly prohibited.Bryophyllum (see below) [4]. While these reviews describe various compounds and bioactivities, none of them addresses the pharmacological and clinical data that support the therapeutic use of Bryophyllum preparations in European countries. The present review focuses on B. pinnatum, but the few data available on Bryophyllum daigremontianum, Bryophyllum delagoense, and the hybrid Bryophyllum daigremontianum x tubiflorum have also been included. The German homeopathic pharmacopeia (HAB) 2014 [5] lists the two species B. pinnatum and B. daigremontianum as officinal in its monography "Bryophyllum Rh", and both have been used in AM. B. delagoense was introduced in the 1980s as an anthroposophic medicinal product in Germany, primarily for sedative purposes (Personal communication, Dr. med. Siegward-M. Elsas, see Acknowledgments). Botany

Optimization of Aqueous Extraction from Kalanchoe pinnata Leaves to Obtain the Highest Content of an Anti‐inflammatory Flavonoid using a Response Surface Model

“…Various herbal preparations using aqueous extracts of leaves from K. pinnata are used worldwide; especially in Anthroposophic medicine in Germany, Switzerland and Brazil (Fürer et al ., ; Hosomi et al ., ; Simões‐Wüst et al ., ). Chewable tablets manufactured from K. pinnata leaves (350 mg, 50% leaf pressed juice on lactose, corresponding to 175 mg of fresh plant per tablet) are recommended for the treatment of sleep disorders, anxiety, agitation, exhaustion and recurrent inflammatory conditions (Hosomi et al ., ; Simões‐Wüst et al ., ).…”

Two Randomised Clinical Trials on the Use of <b><i>Bryophyllum pinnatum</i></b> in Preterm Labour: Results after Early Discontinuation

“…More recently, an observational study was performed [11]. The use of B. pinnatum as a tocolytic agent is supported by experimental evidence [12]. The available evidence demanded prospective, randomised trials to characterise efficacy.…”

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“…Kalanchoe pinnata (Lmk) Pers is not toxic 23 and also safe for maternity since it reduces the uterine contractility 24 . This "miracle plant" is widely used as traditional in Africa and Bangladesh for many purposes 25,26 . TMPD >98% purity (Pristane) with the code number of Sigma-P2870 was obtained from SigmaAldrich supplier in Singapore.…”