BTK inhibition potentiates anti-PD-L1 treatment in murine melanoma: potential role for MDSC modulation in immunotherapy

Revealing the potential bioactive components and mechanism of Qianhua Gout Capsules in the treatment of gouty arthritis through network pharmacology, molecular docking and pharmacodynamic study strategies

“…Research has indicated a significant correlation between MMP9 and the IL-17 signaling pathway. By enhancing IL-17 signaling pathway transduction, drugs can potentially exhibit anti-inflammatory effects by upregulating the downstream target MMP9 [ 52 , 71 ]. PPARG, a nuclear hormone receptor, is found in many tissue cells and is important for controlling adipose tissue differentiation, metabolism, and protecting bones and joints.…”