BTX-A Rejuvenation: Regional Botulinum Toxin-A Injection of the Platysma in Patients with Facial Sagging

A retrospective analysis of the uses of BoNT‐A in daily dermatological practice

“…BoNT‐A treatment for masseter hypertrophy was slightly more preferred by male patients (58%) in one study 13 . A 62.1% female dominance for BoNT‐A treatment addressing the platysmal bands was observed in a study previously 14 . A previous study showed that there was no difference in terms of gender in the BoNT‐A treatment for hyperhidrosis, both axillary and palmoplantar types 15 .…”

“…13 A 62.1% female dominance for BoNT-A treatment addressing the platysmal bands was observed in a study previously. 14 A previous study showed that there was no difference in terms of gender in the BoNT-A treatment for hyperhidrosis, both axillary and palmoplantar types. 15 To our knowledge, ours is the first study to determine the gender prevalences according to the treatment area, and we report that there is no treatment area preference in terms of gender.…”

“…However, previous literature has shown that the treatment results of platysmal BoNT-A injections are more satisfying in younger patients with platysmal muscle hyperactivity whose skin elasticity is still retained. 3,14 We can conclude that dermatologists should encourage patients for platysmal BoNT-A treatment at earlier ages in order to achieve more satisfying results.…”

Mexiletine Can Be Used to Prevent and Reduce Facial Wrinkles

“…2 At present, plastic surgery clinical treatment of facial wrinkles mainly use Botulinum Toxin A injection method. 3 Botulinum Toxin A acts on the peripheral motor nerve endings, inhibits the release of acetylcholine from presynaptic membrane, relaxes local muscles, and exerts wrinkles removal effect. 4 It has been found that mexiletine also relaxes the striated muscles and has good antioxidant properties.…”

“…Facial expression muscle contraction and facial skin aging and relaxation are the main causes of facial wrinkles 2 . At present, plastic surgery clinical treatment of facial wrinkles mainly use Botulinum Toxin A injection method 3 . Botulinum Toxin A acts on the peripheral motor nerve endings, inhibits the release of acetylcholine from presynaptic membrane, relaxes local muscles, and exerts wrinkles removal effect 4 .…”