Buccal mucosa graft urethroplasty in a case of urethral amyloidosis presenting with long anterior urethral stricture

Kurbatov, D G; Dubskiy, S A; Lepetukhin, A E; Stojanovic, Borko; Djordjević, Miroslav L.

doi:10.5489/cuaj.2957

Cited by 3 publications

(1 citation statement)

References 11 publications

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“…Pedicled penile skin flaps or buccal mucosa grafts are the most common materials used during urethroplasty due to their higher graft survival rates on the urethra ( 12 ). However, it is important to confirm that amyloidosis is localized only in the urethra, as the lesions may also affect the buccal mucosa and penile skin ( 13 ).…”

Section: Discussionmentioning

confidence: 99%

Benefits of urethroplasty for managing urethral amyloidosis: A case report

Yao

Yuan

Fang

et al. 2017

Experimental and Therapeutic Medicine

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Urethral amyloidosis is a rare condition in which eosinophilic amyloid proteins are deposited in the urethra. Only a small number of reports on urethral amyloidosis have been published. Increased interest has been associated with this disease due to its clinical similarities with urothelial carcinoma. A biopsy of the lesion and a histological examination are essential for the correct diagnosis. Conservative management has been suggested by various urologists as the optimal treatment approach for urethral amyloidosis; however, recurrence and urethral stricture are common, and typically further treatment is required. Urethroplasty has been used in a limited number of urethral amyloidosis cases, with beneficial short-term outcomes; however, long-term follow-up data are lacking. The present case report describes the cases of 2 patients with urethral amyloidosis who underwent urethroplasty without recurrence or progression for >2 years. These findings indicate that urethroplasty is beneficial for the long-term management of urethral amyloidosis.

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Section: Discussionmentioning

confidence: 99%

Benefits of urethroplasty for managing urethral amyloidosis: A case report

Yao

Yuan

Fang

et al. 2017

Experimental and Therapeutic Medicine

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Primary localized amyloidosis presenting as urethral stricture: An important differential diagnosis on frozen section

Isaacson

Dahmoush

Robinson

2020

Human Pathology: Case Reports

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Primary isolated amyloidosis of the urethra: a case report

Kwizera¹,

Uystepruyst²,

Bollens³

et al. 2020

EJMCR

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Background: Amyloidosis is a tissue protein deposition. Urethral amyloidosis is rare. Clinical presentation includes hematuria, obstructive urinary symptoms, urethritis-like symptoms, urethral discharge, or a palpable penile/urethral mass. The diagnosis is made by urethro-cystoscopy and biopsy. Case Presentation: We report the case of a 38-year-old man with a medical history of recurrent urinary tract infections, urethral discharge, and a palpable bulbar urethral mass. Urethral biopsies confirmed the urethral amyloidosis. The treatment was endoscopic urethral dilatation. Conclusion: Urethral amyloidosis is a rare condition and a challenging diagnosis. Urethroscopy is the best method for diagnosis. Biopsies should be done to exclude malignancy.

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Buccal mucosa graft urethroplasty in a case of urethral amyloidosis presenting with long anterior urethral stricture

Cited by 3 publications

References 11 publications

Benefits of urethroplasty for managing urethral amyloidosis: A case report

Benefits of urethroplasty for managing urethral amyloidosis: A case report

Primary localized amyloidosis presenting as urethral stricture: An important differential diagnosis on frozen section

Primary isolated amyloidosis of the urethra: a case report

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