Build-up and release from proactive interference during chronic ethanol consumption in mice: A behavioral and neuroanatomical study

Béracochéa, Daniel; Lescaudron, Laurent; Tako, Antoine; Verna, A.; Jaffard, Robert

doi:10.1016/0166-4328(87)90045-3

Cited by 50 publications

(17 citation statements)

References 28 publications

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“…Moderate cell loss was also observed in the ATH nuclei (−12% compared with controls) and in the CA1 of the hippocampus (−13% compared with alcohol controls) (Lescaudron et al . 1984; Beracochea et al . 1987a).…”

Section: Resultsmentioning

confidence: 99%

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Deficits of spatial and non‐spatial memory and of auditory fear conditioning following anterior thalamic lesions in mice: comparison with chronic alcohol consumption

Célérier

Ognard

Decorte

et al. 2000

Eur J of Neuroscience

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This study was aimed at determining (i) whether or not bilateral subtotal lesions of the anterior thalamic nuclei (ATH) in rodents produced memory deficits for spatial and/or non-spatial information and of auditory fear conditioning, and (ii) if these eventual deficits resemble those produced by chronic alcohol consumption (CAC). Working memory was assessed using both spatial (spontaneous alternation) and non-spatial (temporal alternation) delayed response tasks. Results showed that ATH lesions induced delay-dependent memory impairments in both spatial and non-spatial alternation tasks, as well as a decreased level of auditory and background contextual fear conditioning compared with respective controls. CAC did not induce accelerated rate of forgetting in the spatial and non-spatial tasks, but increased the vulnerability to interference in the spatial task. CAC impaired only background contextual fear conditioning. We conclude that ATH nuclei are involved in the maintenance of information over time, regardless of the nature (spatial vs. non-spatial) of the information, and play a role in associative processes for both unimodal (the tone) and polymodal (contextual) information. In contrast, ATH dysfunction does not account for the memory disorders induced by the CAC treatment. Our results contribute to showing that the functional overlap between the structures comprising the hippocampo-mamillo-thalamic pathway is only partial.

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Section: Resultsmentioning

confidence: 99%

“…Questions also remain concerning the role of ATH dysfunction in the amnesia produced by a chronic alcohol consumption (CAC). Indeed, we previously showed that CAC produced memory deficits associated with damage or dysfunction of the mammillary bodies (Beracochea et al . 1987a; Bontempi et al .…”

Section: Introductionmentioning

confidence: 99%

Deficits of spatial and non‐spatial memory and of auditory fear conditioning following anterior thalamic lesions in mice: comparison with chronic alcohol consumption

Célérier

Ognard

Decorte

et al. 2000

Eur J of Neuroscience

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“…Working memory was assessed using the T-maze sequential alternation task (Beracochea, Lescaudron, Tako, Verna, & Jaffard, 1987). Mice performed 10 successive trials.…”

Section: T-maze Testmentioning

confidence: 99%

Gliovascular changes precede white matter damage and long‐term disorders in juvenile mild closed head injury

Rodriguez‐Grande

Obenaus

Ichkova

et al. 2018

Glia

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Traumatic brain injury (TBI) is a leading cause of hospital visits in pediatric patients and often leads to long-term disorders even in cases of mild severity. White matter (WM) alterations are commonly observed in patients months or years after the injury assessed by magnetic resonance imaging (MRI), but little is known about WM pathophysiology early after mild pediatric TBI. To evaluate the status of the gliovascular unit in this context, mild TBI was induced in postnatal-day 17 mice using a closed head injury model with two grades of severity (G1, G2). G2 resulted in significant WM edema (increased T2-signal) and BBB damage (IgG-extravasation immunostaining) whereas decreased T2 and the increased levels of astrocytic water-channel AQP4 were observed in G1 mice 1 day post-injury. Both severities induced astrogliosis (GFAP immunolabeling). No changes in myelin and neurofilament were detected at this acute time point. One month after injury G2 mice exhibited diffusion tensor imaging MRI alterations (decreased fractional anisotropy) accompanied by decreased neurofilament staining in the WM. Both severities induced behavioral impairments at this time point. In conclusion, long-term deficits and WM changes similar to those found after clinical TBI are preceded by distinct early gliovascular phenotype alterations after juvenile mild TBI, revealing AQP4 as a potential candidate for severity-based treatments.

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“…En effet, on peut supposer que la réponse à l'essai n dépendant de la mémoire du bras visité à l'essai (n-1) peut être perturbée par les souvenirs des choix antérieurs (de 1 à n-2). L'épreuve permet donc d'étudier la sensibilité aux interférences proactives (Beracochea et al,1987), comme observé chez les témoins à l'essai 3. En outre, les résultats ont révélé qu'après 3 mois de consommation de koutoukou, au cours des épreuves d'alternances sérielles spontanées, l'augmentation du nombre d'essais entraine une diminution significative du taux d'alternances chez les animaux soumis à l'alcoolisation chronique.…”

Section: Methodesunclassified

Effets d’une consommation prolongée de «koutoukou» (boisson alcoolique artisanale) sur la mémoire spatiale chez la souris.

Badjo¹,

Diboh²,

Gbalou³

et al. 2017

J. App. Bioscience.

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Badjo et al., J. Appl. Biosci. 2017 Effets d'une consommation prolongée de «koutoukou» (boisson alcoolique artisanale) sur la mémoire spatiale chez la souris. 11557Journal of Applied Biosciences 116: 11557-11565 ISSN 1997-5902 Effets d'une consommation prolongée de «koutoukou» (boisson alcoolique artisanale) sur la mémoire spatiale chez la souris. ABSTRACT Objective: The aim of this study was to determine the effects of "koutoukou", a traditional drink after the fermented sap of distilling oil palm (Elaeis guineensis) on memory skills Methodology and Results: 62 Swiss mice of which 22 controls and 40 experimental animals were subjected to a T-labyrinth test. The controls consumed ordinary water as a drink. The experimental animals were divided into two groups: 20 koutoukou alcoholic mice for 3 months and 20 other koutoukou alcoholic mice for 6 months. Comparison of the serial spontaneous alternation between the two experimental groups showed a more marked decrease in this rate (alternation) in the alcoholic animals during 6 months. As for the delayed alternation of tests, they showed that this rate drops significantly at 6 am (the time between the acquisition phase and the return phase) in mice treated koutoukou for 6 months against 24 hours in those alcohol for 3 month. Conclusion and application of results: Chronic koutoukou consumption leads to deficits in both working memory and episodic memory.

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Build-up and release from proactive interference during chronic ethanol consumption in mice: A behavioral and neuroanatomical study

Cited by 50 publications

References 28 publications

Deficits of spatial and non‐spatial memory and of auditory fear conditioning following anterior thalamic lesions in mice: comparison with chronic alcohol consumption

Deficits of spatial and non‐spatial memory and of auditory fear conditioning following anterior thalamic lesions in mice: comparison with chronic alcohol consumption

Gliovascular changes precede white matter damage and long‐term disorders in juvenile mild closed head injury

Effets d’une consommation prolongée de «koutoukou» (boisson alcoolique artisanale) sur la mémoire spatiale chez la souris.

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