Building Cross-Country Networks for Laboratory Capacity and Improvement

Schneidman, Miriam; Matu, Martin; Nkengasong, John N.; Githui, W.A.; Kalyesubula-Kibuuka, Simeon; Silva, Kelly Araujo

doi:10.1016/j.cll.2017.10.009

Cited by 4 publications

(4 citation statements)

References 5 publications

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Section: Discussionmentioning

confidence: 99%

“…One source suggested implementation of a regional peer audit mechanism, which could be an effective tool for facilitating cross-country learning and enhancing the performance of staff in the region. 75 Conflict and political instability were identified as the most significant challenges to establishing regional collaborations. 31 Another is the sustainability of funding, which may be improved by visits from external donors to regional staff, encouraging feedback on activities and responding to staff concerns.…”

Section: Key Findingsmentioning

confidence: 99%

See 1 more Smart Citation

Operationalising Regional Cooperation for Infectious Disease Control: A Scoping Review of Regional Disease Control Bodies and Networks

Durrance-Bagale

Marzouk

Agarwal

et al. 2021

Int J Health Policy Manag

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Background: The rapid spread of the COVID-19 pandemic demonstrates the value of regional cooperation in infectious disease prevention and control. We explored the literature on regional infectious disease control bodies, to identify lessons, barriers and enablers to inform operationalisation of a regional infectious disease control body or network in southeast Asia. Methods: We conducted a scoping review to examine existing literature on regional infectious disease control bodies and networks, and to identify lessons that can be learned that will be useful for operationalisation of a regional infectious disease control body such as the ASEAN Center for Public Health Emergency and Emerging Diseases. Results: Of the 57 articles included, 53 (93%) were in English, with two (3%) in Spanish and one (2%) each in Dutch and French. Most were commentaries or review articles describing programme initiatives. Sixteen (28%) publications focused on organisations in the Asian continent, with 14 (25%) focused on Africa, and 14 (24%) primarily focused on the European region. Key lessons focused on organisational factors, diagnosis and detection, human resources, communication, accreditation, funding, and sustainability. Enablers and constraints were consistent across regions/organisations. A clear understanding of the regional context, budgets, cultural or language issues, staffing capacity and governmental priorities, is pivotal. An initial workshop inclusive of the various bodies involved in the design, implementation, monitoring or evaluation of programmes is essential. Clear governance structure, with individual responsibilities clear from the beginning, will reduce friction. Secure, long-term funding is also a key aspect of the success of any programme. Conclusion: Operationalisation of regional infectious disease bodies and networks is complicated, but with extensive groundwork, and focus on organisational factors, diagnosis and detection, human resources, communication, accreditation, funding, and sustainability, it is achievable. Ways to promote success are to include as many stakeholders as possible from the beginning, to ensure that context-specific factors are considered, and to encourage employees through capacity building and mentoring, to ensure they feel valued and reduce staff turnover.

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Section: Discussionmentioning

confidence: 99%

Section: Key Findingsmentioning

confidence: 99%

Operationalising Regional Cooperation for Infectious Disease Control: A Scoping Review of Regional Disease Control Bodies and Networks

Durrance-Bagale

Marzouk

Agarwal

et al. 2021

Int J Health Policy Manag

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“…Adequate microbiology capacity is vital not only for the identification and targeted treatment of individual patients’ infection but also to inform local empiric therapeutic choices and pharmaceutical purchasing. One strategy to expand access to high-quality diagnostics is the development of regional reference laboratory networks [ 78 , 79 ]. Additionally, as rapid diagnostic testing becomes more available and affordable, this may play a more important role in the initial management of sepsis.…”

Section: Practical Steps To Reduce the Global Burden Of Sepsismentioning

confidence: 99%

The global burden of sepsis: barriers and potential solutions

et al. 2018

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Sepsis is a major contributor to the global burden of disease. The majority of sepsis cases and deaths are estimated to occur in low and middle-income countries. Barriers to reducing the global burden of sepsis include difficulty quantifying attributable morbidity and mortality, low awareness, poverty and health inequity, and under-resourced and low-resilience public health and acute health care delivery systems. Important differences in the populations at risk, infecting pathogens, and clinical capacity to manage sepsis in high and low-resource settings necessitate context-specific approaches to this significant problem. We review these challenges and propose strategies to overcome them. These strategies include strengthening health systems, accurately identifying and quantifying sepsis cases, conducting inclusive research, establishing data-driven and context-specific management guidelines, promoting creative clinical interventions, and advocacy.

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“…Recently, remarkable efforts have been invested in building laboratory infrastructure, with reported preliminary success. 14 , 15 Despite those efforts, Rwanda, like many other developing countries, is still lagging in some of the key areas of preparedness for EID epidemics. For example, as highlighted in the recently developed Rwanda One Health policy, 16 human resource capacity in the laboratories is still deficient.…”

Section: Introductionmentioning

confidence: 99%

A systematic review to describe patterns of animal and human viral research in Rwanda

Dutuze

Byukusenge

Shyaka

et al. 2022

International Health

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Rwanda is located in the Central East African region where several viral pathogens with global importance were originally described, including human immunodeficiency virus (HIV), Ebola, Zika, Rift Valley Fever (RVF), dengue and a long list of other neglected tropical viral pathogens. Due to many factors, this region has the potential to become a global hotspot for viral emergence. In Rwanda, viral diseases are underreported and the question is whether this is due to the absence of these viruses or a lack of investigation. Like many developing countries, capabilities in Rwanda need improvement despite research efforts throughout the years. This review describes the status of human and animal virus research in Rwanda and identifies relevant research and operational gaps. A comprehensive search was conducted in PubMed for virus research in Rwanda: 233 primary studies on viruses/viral diseases are indexed with connection to Rwanda. From 1958 to 2020, yearly publications generally increased and HIV/acquired immunodeficiency syndrome is the most studied virus. Compared with human viruses, few studies focus on animal and/or zoonotic viruses. The occurrence of the current severe acute respiratory syndrome coronavirus 2 pandemic shows strengthening warning and surveillance systems is critical to efficient preparedness and response. We recommend investment in human capacity, laboratory facilities and research to inform policy for viral surveillance in Rwanda.

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Building Cross-Country Networks for Laboratory Capacity and Improvement

Cited by 4 publications

References 5 publications

Operationalising Regional Cooperation for Infectious Disease Control: A Scoping Review of Regional Disease Control Bodies and Networks

Operationalising Regional Cooperation for Infectious Disease Control: A Scoping Review of Regional Disease Control Bodies and Networks

The global burden of sepsis: barriers and potential solutions

A systematic review to describe patterns of animal and human viral research in Rwanda

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