The biblical narrative of the Tower of Babel serves as a metaphor for the challenges and divisions created by the multiplicity and diversity of languages. According to the story, the construction of the Tower of Babel was seen as an act of defiance against divine will, leading to the creation of multiple languages, subsequently fragmenting humanity into groups unable to understand each other. This historical allegory underscores the importance of overcoming linguistic barriers to foster collaboration for the benefit of humankind. Linguists characterize language as a social determinant of health [1] that could be a barrier in healthcare leading to miscommunication between the healthcare professional and the patient. The latter may not have access to adequate healthcare services if they do not speak the language of the service providers, decreasing the quality of healthcare delivery and patient safety [2]. At the global level, non-English-speaking scientists have limited access to international conferences, significant funding, and scientific publications that are mainly in English [3].In the field of global health, effective collaboration is crucial for implementing inclusive projects that meet stakeholder goals and have a tangible impact on the communities they aim to enhance, ultimately improving quality of life. Collaboration is at the top of the four C pyramid and is built upon a foundation of trust (Confidence), Communication, understanding (Comprehension), and the collective pursuit of a common goal (Fig 1). These elements are critical for successful partnerships. Unfortunately, language disparities can hinder these foundational layers, impacting trust, limiting communication, obstructing understanding, and blocking collaboration.