Dengue disease incidence is related with the construction of a house roof, which is an Aedes mosquito habitat. This study was conducted to classify pitch roof (PR) and flat roof (FR) surfaces using pan-sharpened Worldview 2 to identify dengue disease patterns (DDPs) and their association with DDP. A Supervised Minimum Distance classifier was applied to 653 training data from image object segmentations: PR (81 polygons), FR (50), and non-roof (NR) class (522). Ground validation of 272 pixels (52 for PR, 51 for FR, and 169 for NR) was done using a global positioning system (GPS) tool. Getis-Ord score pattern analysis was applied to 1154 dengue disease incidence with address-approach-based data with weighted temporal value of 28 days within a 1194 m spatial radius. We used ordinary least squares (OLS) and geographically weighted regression (GWR) to assess