“…PTSD is known to be both predicted by and is a predictor of psychiatric comorbidity, and their association is bidirectional (Geng et al., 2019). Our hypothesis that severity is related to PTSD is based on a rich scientific literature showing that elevated psychiatric comorbidity is highly linked to the presence of prior trauma and in particular a diagnosis of PTSD (Brady et al., 2000; Brewerton, 2002, 2006, 2007; Dansky et al., 2000; Goldstein et al., 2016; Kessler et al., 1995; Kilpatrick et al., 2003; McLaughlin et al., 2013; Merikangas et al., 2010; Qassem et al., 2021). Furthermore, adolescent PTSD is characterized by developmental abnormalities in frontolimbic circuitry that may contribute to increasing threat reactivity, weaker emotion regulation and higher rates of internalizing symptoms, such as anxiety and depression (Herringa, 2017; Herringa et al., 2013).…”