Bulk nanostructure of a deep eutectic solvent with an amphiphilic hydrogen bond donor

Abstract

Neutron diffraction with empirical potential structure refinement shows that the deep eutectic solvent 1 : 4 choline chloride : butyric acid is an amphiphilically nanostructured liquid.

Bulk Nanostructure of Mixtures of Choline Arginate, Choline Lysinate, and Water

“…Of these g ij ( r )­s, the highest coordination number is between the Ch + nitrogen and water oxygen, revealing that water tends to hydrate the Ch + charge center. The strong interaction between water and Ch + is also observed in aqueous mixtures of cholinium-deep eutectic solvents. − …”

Evidence for an L3 phase in ternary deep eutectics: composition-induced L3-to-Lα transition of AOT

“…36 McDonald et al have shown small-angle nanostructure in binary DES engineered to contain long alkyl subunits, 37 which has recently also been shown for choline chloride : butyric acid DES. 38 However, the question of nanostructure in archetypal, non-amphiphilic DES such as ChCl-urea, remains open and debated, and the same is true for ternary DES; 39 this issue is therefore important to resolve considering the popularity of these systems. Since ChCl-urea is the most widely used DES in studies of amphiphile self-assembly, we have chosen this system as a model starting point towards myriad future studies, expanding on the possibilities of solute organisation in such solvents.…”