In this work, we shortly review the role and properties of hyperons in finite and infinite nuclear systems such as hypernuclei and neutron stars. Particularly, we describe different production mechanisms of hypernuclei, discuss some aspects of their γ-ray spectroscopy and their weak decay modes, and give a few strokes on their theoretical description. We reexamine also the role played by hyperons on the properties of neutron and proto-neutron stars with a special emphasis on the well-known “hyperon puzzle”, of which we discuss some of the solutions that have been proposed to tackle this problem. Finally, we review the role of hyperons on the cooling properties of newly born neutron stars and on the so-called r-mode instability.