Bullous keratopathy treated with honey

Sethi, Harinder Singh; Harminder, K

doi:10.1111/j.1600-0420.2005.00412.x

Cited by 8 publications

(2 citation statements)

References 5 publications

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“…There are no studies of treating thyroid disease patients with honey eye drops. The effect of honey was noted in patients with bullous keratopathy by Sethi and Rai (2005) [11]. Their studies have shown that honey drops have good anti-toxic and anti-inflammatory features, they regenerate of the tissues.…”

Section: Resultsmentioning

confidence: 99%

“…Until recent times, there have been studies about honey medical use because of its antibacterial activity. In medical literature, there are reports on honey used for the treatment of burn wounds, bullous keratopathy [10,11]. The healing, regeneration and stimulation of the immune system by honey, its antibacterial, debriding, antiinflammatory action allow to cure the ocular and palpebral burns and wounds, to reduce inflammation, swelling, and pain.…”

Section: Introductionmentioning

confidence: 99%

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Investigation of ocular changes in children and young people with thyroid diseases before and after the treatment with 20 % honey solution eye drops

2012

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The objective of the study was to investigate ocular changes in children and young patients with thyroid diseases before and after the treatment with 20 % honey solution eye drops. In total, 33 patients with thyroid diseases and corneal, conjunctival changes were examined. There were 25 girls and 8 boys aged 6 to 29.5 years, mean age 13.2 ± 3.7 years; 17 patients were treated with 20 % honey solution eye drops and 16 patients received artificial tears (three times a day, for 3 weeks). There was evaluated the state of eye conjunctiva and cornea, visual acuity, proptosis before and after the course of treatment. All patients underwent a complete ophthalmic examination including bestcorrected Snellen visual acuity, slit-lamp, corneal sensitivity investigations and the Hertel exophthalmometry. The treatment with 20  honey eye drops reduced complaints of patients (photophobia, itching, foreign body sensation, tearing, and the eye ball pain), statistically significant by improved visual acuity, the status of the conjunctiva (redness, swelling) and cornea (fluorescein staining, corneal sensitivity and erosions) in comparison with those patients who used artificial tears. There was no change in proptosis measurements after the treatment. We have found a more positive effect of 20  honey solution eye drops on the state of the conjunctiva and cornea in patients with thyroid diseases when the treatment had been started at the early period of thyroid diseases when there had been no corneal damages. The 20  honey solution eye drops reduced the complaints of patients, statistically significant by improved their visual acuity, the status of the conjunctiva (redness, swelling) and cornea. Honey eye drops may be used to prevent conjunctival and corneal complications in patients with thyroid diseases and corneal, conjunctival changes.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Investigation of ocular changes in children and young people with thyroid diseases before and after the treatment with 20 % honey solution eye drops

2012

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Honey Prophylaxis Reduces the Risk of Endophthalmitis During Perioperative Period of Eye Surgery

Cernák

Majtánová

Cernák

et al. 2011

Phytotherapy Research

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Endophthalmitis following eye surgery remains a rare but serious complication. Topical fluoroquinolones have been used as prophylactic agents against endophthalmitis. However, the emerging resistance of ocular pathogens to fluoroquinolones may preclude their routine use. Honey, a natural antimicrobial product with wound healing properties, is a promising candidate for the prophylaxis of endophthalmitis. The goal of this study was to determine whether 25% (w/v) honey solution is effective in eradicating bacterial ocular pathogens in the perioperative period in patients scheduled for cataract surgery or vitrectomy, and to compare its efficacy to 0.3% ofloxacin. In this pilot study, 101 patients were randomized to honey (n = 49) or ofloxacin (n = 52) treatment. In both groups, eye drops were administered five times a day for 7 days before and 5 days after surgery. Before administration of the antibacterial agents, 18 and 25 isolates were detected in the ofloxacin and honey group, respectively. After 7 days of administration, four isolates (coagulase-negative Staphylococcus) were detected in each therapeutic group. No significant difference in antibacterial effect was found between groups. These results indicate that honey may act as a prophylactic agent of endophthalmitis; however, further studies are needed to characterize its ocular penetration properties.

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