Bullous keratopathy treated with honey

Sethi, Harinder Singh; Harminder, K

doi:10.1111/j.1600-0420.2005.00411.x

Cited by 7 publications

(5 citation statements)

References 1 publication

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“…Healing of bacterial corneal wound has been reported by honey. Honey can also probably be effective in improving the scars after infections [19, 20]. The anti-inflammatory effect of honey has caused it to be used in the treatment of blepharitis (inflammation of the eyelid margins) and keratitis (corneal inflammation) [21].…”

Section: Discussionmentioning

confidence: 99%

A Double Blind Clinical Trial on the Efficacy of Honey Drop in Vernal Keratoconjunctivitis

Salehi

Jabarzare

Neurmohamadi

et al. 2014

Evidence-Based Complementary and Alternative Medicine

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Purpose. This trial was designed to evaluate the efficacy and safety of topical honey eye drops in patients with diagnosed VKC. Methods. This clinical trial was conducted on 60 patients with diagnosed VKC. The patients were selected and randomly allocated between two groups of 30. Patients in two groups received honey eye drop (60% in artificial tear) or placebo, other than cromolyn and fluorometholone 1% eye drops, to be used topically in each eye, four times per day. The patients were examined with slit lamp and torch at baseline and the follow-up visits on the 1st, 3rd, and 6th months of the study for redness, limbal papillae, and intraocular pressure. Results. Out of 60 patients who completed the study, 19 patients (31.7%) were female. There was significant increase in eye pressure and reduction in redness as well as limbal papillae, following the consumption of the honey drop in honey group compared to placebo control group (P < 0.05). At the end of trial, one patient in honey group and 7 ones in placebo group had limbal papillae (P < 0.05). Conclusion. Topical honey eye drops, when used along with Cromolyn and Fluorometholone eye drops, might be beneficial for the treatment of VKC.

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Section: Discussionmentioning

confidence: 99%

A Double Blind Clinical Trial on the Efficacy of Honey Drop in Vernal Keratoconjunctivitis

Salehi

Jabarzare

Neurmohamadi

et al. 2014

Evidence-Based Complementary and Alternative Medicine

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“…[ 33 ] Moreover, its topical application has been shown to treat corneal abrasions and endotoxin-induced keratitis in an animal model. [ 33 ] It is reported that honey is effective in bullous keratopathy[ 34 ] and corneal epithelial wound healing. [ 35 ] It also has beneficial effects in patients with dry eyes.…”

Section: Honeymentioning

confidence: 99%

Ocular Complications Resulting from the Use of Traditional Herbal Medicine in Central Saudi Arabia

Al-Ghadeer

Al-Amry

2021

Middle East African Journal of Ophthalmology

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The present paper reviewed the ocular complications resulting from the use of traditional eye medicine in Central Saudi Arabia. We performed a literature search of the PubMed database using the keywords “traditional medicine,” “herbal medicine,” “ocular injuries,” and “visual impairments,” covering all years available for peer-reviewed full-text articles, letters, and review chapters of books. An additional search was performed in Google Scholar. All published materials were in English. Several ocular symptoms and disorders, including conjunctival cicatrization, symblepharon formation, obliteration of the fornices and the canaliculi, keratinization of the cornea, dryness, central corneal thinning, and corneal epithelial defect, have been associated with the use of traditional herbal medicine. In addition, the use of traditional eye medicine may result in corneal edema, opacity, ulceration, and perforation. Early recognition of ocular injuries could avoid or at least delay long-term sequelae. Ophthalmologists should be aware of the side effects of traditional remedies. Furthermore, public education, early detection of symptoms, and timely intervention may prevent permanent damage to the eyes.

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“…One area in which its use appears promising is ophthalmology. There is some evidence that honey has been used successfully in the treatment of dry eye syndrome (Albietz and Lenton, ; Jankauskiene et al , ), bullous keratopathy (Sethi and Rai, ) and in the treatment of opacities of the cornea after herpetic keratitis (Mozherenkov and Prokofjeva, ). Furthermore, it has been shown that honey reduces redness, swelling and the time taken to eradicate ocular bacterial infections of the conjunctiva (Al‐Waili, ).…”

Section: Introductionmentioning

confidence: 99%

Honey Prophylaxis Reduces the Risk of Endophthalmitis During Perioperative Period of Eye Surgery

Cernák

Majtánová

Cernák

et al. 2011

Phytotherapy Research

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Endophthalmitis following eye surgery remains a rare but serious complication. Topical fluoroquinolones have been used as prophylactic agents against endophthalmitis. However, the emerging resistance of ocular pathogens to fluoroquinolones may preclude their routine use. Honey, a natural antimicrobial product with wound healing properties, is a promising candidate for the prophylaxis of endophthalmitis. The goal of this study was to determine whether 25% (w/v) honey solution is effective in eradicating bacterial ocular pathogens in the perioperative period in patients scheduled for cataract surgery or vitrectomy, and to compare its efficacy to 0.3% ofloxacin. In this pilot study, 101 patients were randomized to honey (n = 49) or ofloxacin (n = 52) treatment. In both groups, eye drops were administered five times a day for 7 days before and 5 days after surgery. Before administration of the antibacterial agents, 18 and 25 isolates were detected in the ofloxacin and honey group, respectively. After 7 days of administration, four isolates (coagulase-negative Staphylococcus) were detected in each therapeutic group. No significant difference in antibacterial effect was found between groups. These results indicate that honey may act as a prophylactic agent of endophthalmitis; however, further studies are needed to characterize its ocular penetration properties.

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Bullous keratopathy treated with honey

Cited by 7 publications

References 1 publication

A Double Blind Clinical Trial on the Efficacy of Honey Drop in Vernal Keratoconjunctivitis

A Double Blind Clinical Trial on the Efficacy of Honey Drop in Vernal Keratoconjunctivitis

Ocular Complications Resulting from the Use of Traditional Herbal Medicine in Central Saudi Arabia

Honey Prophylaxis Reduces the Risk of Endophthalmitis During Perioperative Period of Eye Surgery

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