Burden of cardiovascular disease attributable to long-term exposure to ambient PM2.5 concentration and the cost–benefit analysis for the optimal control level

Chen, Chu-Chih; Wang, Yin-Ru; Liu, Jhi-Shin; Chang, Hsing-Yi; Guo, Yang; Chen, Pau‐Chung

doi:10.1016/j.scitotenv.2023.164767

Cited by 8 publications

(2 citation statements)

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“…PM 2.5 is a mixed particulate consisting of a mixture of solid particles and liquid droplets, which can contain a variety of chemical compounds including sulfates, nitrates, organic compounds, metals, and other pollutants [ 4 ]. Long-term exposure to concentrations of ambient PM2.5 is known to be associated with many health effects, including cardiopulmonary disorders, diabetes mellitus, and adverse health outcomes [ 5 , 6 ]. Although existing researches have indicated that air pollution was significantly associated with dyslipidemia, there are some limitations [ 4 , 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

“…Long-term exposure to ambient PM 2.5 is known to be associated with many respiratory and circulatory diseases [ 6 , 9 , 10 ]. The HDL level, being a crucial physiological indicator among middle-aged and older individuals holds significant implications for their cardiovascular health, thereby impacting the economic and medical burdens borne by our society [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

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The association between long-term exposure to ambient PM2.5 and high-density lipoprotein cholesterol level among chinese middle-aged and older adults

Liu,

Qiao

2024

BMC Cardiovasc Disord

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Background Recently, the impact of PM2.5 on human health has been intensively studied, especially the respiratory system. High-density lipoprotein plays a crucial role in removing excess cholesterol from cells and transporting it to the liver for excretion. However, the effects of ambient PM2.5 on high-density lipoprotein (HDL) level have not been further studied. Our research aims to investigate the potential association between ambient PM2.5 concentrations and high-density lipoprotein (HDL) levels within the middle-aged and older adults in China. Methods We employed data from individuals aged 45 years and above who were participants in Wave 3 of the China Health and Retirement Longitudinal Study (CHARLS). The high-quality, high-resolution PM2.5 exposure concentration data for each participant were obtained from the ChinaHighAirPollutants (CHAP) dataset, while the HDL levels were derived from blood samples collected during CHARLS Wave 3. This analysis constitutes a cross-sectional study involving a total of 12,519 participants. To investigate associations, we conducted multivariate linear regression analysis, supplemented by subgroup analysis. Results In this cross-sectional investigation, we discerned a negative association between prolonged exposure to ambient PM2.5 constituents and high-density lipoprotein (HDL) levels. The observed correlation between ambient PM2.5 and HDL levels suggests that older individuals residing in areas with elevated PM2.5 concentrations exhibit a reduction in HDL levels (Beta: -0.045; 95% CI: -0.056, -0.035; P < 0.001). Upon adjusting for age in Model I, the Beta coefficient remained consistent at -0.046 (95% CI: -0.056, -0.035; p < 0.001). This association persisted even after accounting for various potential confounding factors (Beta = -0.031, 95% CI: -0.041, -0.021, p < 0.001). Conclusions Our study reveals a statistically significant negative correlation between sustained exposure to higher concentrations of ambient PM2.5 and high-density lipoprotein (HDL) levels among Chinese middle-aged and older individuals.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The association between long-term exposure to ambient PM2.5 and high-density lipoprotein cholesterol level among chinese middle-aged and older adults

Liu,

Qiao

2024

BMC Cardiovasc Disord

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Mapping and visualizing global knowledge on planetary health in the climate change context: a comprehensive exploration of insights, trends, and research priorities

Zyoud,

Zyoud

2024

Discov Sustain

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Climate change presents a substantial global threat to human health and wellbeing. Planetary health, an emerging field, provides a comprehensive framework to comprehend the intricate interplay between ecological stability, human health, and ecosystems, particularly within the context of climate change. This study investigates the planetary health perspective on climate change by exploring global knowledge. The Scopus database is used as the source of data. The analysis encompassed a performance evaluation aimed at scrutinizing both quantitative and qualitative indicators. Visualization techniques utilizing VOSviewer software were deployed to analyze collaboration patterns, co-citation links among prominent knowledge-sharing platforms, and key topics derived from keyword co-occurrence matrices. Additionally, using SciMAT software, the study conducted thematic evolution and intellectual analyses to identify both driving and emerging themes, while also examining coherence among different themes across various periods. The study also explores policy implications, and the relevance of COVID-19 in the context of planetary health and climate change. Through this analysis, 261 relevant publications are identified, with the United States being the leading contributor (90 documents; 34.5% of publications). At the institutional level, the Australian National University secured the top position, representing 4.6% of the total with 12 documents. The Lancet Planetary Health journal was the most prolific source, contributing 15 documents (5.7%). In terms of impact, The Lancet journal held a central position as the most cited source. The primary funding organization was the Wellcome Trust, based in the United Kingdom. Motor themes shaping the future of this field include vector-borne diseases, human demographics, informal settlements, air pollution, carbon footprint of animal-based foods, and pro-environmental attitudes and behaviors. The study underscores the significance of leveraging the momentum surrounding infectious diseases like COVID-19 and the impacts of climate change to advance planetary health concepts. Integration of the social sciences and enhanced multidisciplinary cooperation are crucial for progress. Additionally, increased funding for developing countries, and legislative empowerment are essential to foster further research.

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Associations between long-term ambient PM2.5 exposure and the incidence of cardiopulmonary diseases and diabetes, attributable years lived with disability, and policy implication

Chen,

Wang,

Liu

et al. 2024

Ecotoxicology and Environmental Safety

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Burden of cardiovascular disease attributable to long-term exposure to ambient PM2.5 concentration and the cost–benefit analysis for the optimal control level

Cited by 8 publications

References 38 publications

The association between long-term exposure to ambient PM2.5 and high-density lipoprotein cholesterol level among chinese middle-aged and older adults

The association between long-term exposure to ambient PM2.5 and high-density lipoprotein cholesterol level among chinese middle-aged and older adults

Mapping and visualizing global knowledge on planetary health in the climate change context: a comprehensive exploration of insights, trends, and research priorities

Associations between long-term ambient PM2.5 exposure and the incidence of cardiopulmonary diseases and diabetes, attributable years lived with disability, and policy implication

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