Burden of Disease Associated with Refractory and Unexplained Chronic Cough in Canada: Results from a National Survey

Brister, Danica; Khan, Sana; Abraham, Ted; Laventure, Samuel; Sahakian, Sevag; Juliá, Berta; Satia, Imran

doi:10.1007/s00408-024-00714-1

Cited by 3 publications

(2 citation statements)

References 55 publications

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“…Between July 30, 2021 and September 1, 2021, 49,076 Leger Opinion Panel participants completed the chronic cough screening questionnaire and 6,563 respondents (13.3%) reported currently experiencing a cough most days for the past 8 weeks. One thousand six hundred twenty Canadians (3.3% of all participants and 24.7% of participants with self-reported chronic cough) met entry criteria for RCC/UCC (proportions of patients excluded for each entry criterion are reported in our companion manuscript [ 33 ]). A total of 1,046 individuals (2.1% of total participants, 15.9% of respondents with chronic cough, and 64.6% of eligible participants with chronic cough) completed the online survey.…”

Section: Resultsmentioning

confidence: 99%

“…Thus, the aim of this exploratory study was to evaluate self-reported healthcare professional (HCP) interactions, diagnosis of underlying conditions, treatments, and satisfaction with the management of RCC/UCC in Canadian individuals. In a companion manuscript [ 33 ], we use responses from this survey to evaluate the patient burden associated with current ongoing RCC/UCC. The aim of both analyses was to provide a better understanding of the burden of chronic cough, particularly RCC and UCC, on Canadian individuals and society.…”

Section: Introductionmentioning

confidence: 99%

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Patient satisfaction with the management of refractory and unexplained chronic cough in Canada: Results from a national survey

Khan,

Brister,

Abraham

et al. 2024

PLoS ONE

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Background Chronic cough (persisting for ≥8 weeks) is a common disorder affecting approximately 5 to 10% of adults worldwide that is sometimes refractory to treatment (refractory chronic cough [RCC]) or has no identifiable cause (unexplained chronic cough [UCC]). There is minimal information on the patient’s experience of RCC/UCC in Canada. The aim of this study was to evaluate the patient journey and perceptions related to RCC/UCC management in Canada. Methods Our exploratory study included Canadians in the Leger Opinion Panel and focused on individuals with RCC or UCC. Key entry criteria were: age ≥18 years, cough on most days for ≥8 weeks, no smoking within 1 year, no serious respiratory disease or lung cancer, and not taking angiotensin-converting enzyme inhibitors. Individuals who met entry criteria were invited to complete an approximately 30-minute online survey with questions on demographic characteristics, healthcare professional (HCP) interactions, diagnosis of underlying conditions, current treatments, and satisfaction with HCPs and chronic cough therapies. Results A total of 49,076 individuals completed the chronic cough screening questionnaire (July 30, 2021 to September 1, 2021): 1,620 (3.3%) met entry criteria for RCC or UCC, and 1,046 (2.1%) completed the online survey (mean age of 45 years, 61% female). Most respondents (58%) reported their chronic cough was managed by a general practitioner (GP). Forty-four percent of respondents did not have a diagnosis of an underlying condition for their cough. Breathing tests (39%) and chest imaging (34%) were the most common diagnostic tests. Cough suppressants (18%) were the most frequent current treatment. Respondents were moderately satisfied with their HCPs, but more than half considered their treatment ineffective and 34% had considered no longer seeking medical attention because of a lack of treatment success. Conclusions Individuals with RCC/UCC in Canada are largely unsatisfied with the effectiveness of treatment. Additional HCP education and new treatment options are needed to improve patient satisfaction.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Patient satisfaction with the management of refractory and unexplained chronic cough in Canada: Results from a national survey

Khan,

Brister,

Abraham

et al. 2024

PLoS ONE

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Wenn Husten zum langfristigen Problem wird

Worth

2024

MMW Fortschr Med

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Current opinion in refractory and/or unexplained chronic cough

Misono,

Novaleski

2024

Current Opinion in Otolaryngology &Amp; Head &Amp; Neck Surgery

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Purpose of review Otolaryngologists are vital to successfully managing chronic cough in adults. This review presents updates regarding rapidly evolving concepts in chronic cough. Recent findings Significant growth is occurring in chronic cough research, strengthening the evidence of its major psychosocial impacts. Elucidation of the neural underpinnings of normal and abnormal cough within both the peripheral and central nervous systems highlight the previously underappreciated complexity of cough. Recent clinical practice recommendations emphasize personalized treatment approaches through addressing treatable traits of chronic cough. Investigations are ongoing to better distinguish chronic cough subgroups, and multiple types of important clinical outcome measures are being characterized. Newer research about chronic cough treatment encompasses pharmacologic and nonpharmacologic interventions, including oral and inhaled medications, superior laryngeal nerve blocks, and behavioral therapy. Summary As knowledge about chronic cough in adults continues to expand in both research and clinical practice, otolaryngologists can continue to raise awareness of the role of the larynx in cough and promote ongoing multidisciplinary collaborations. In the coming years, more pharmacologic options and personalized treatment approaches will likely emerge for chronic cough.

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Burden of Disease Associated with Refractory and Unexplained Chronic Cough in Canada: Results from a National Survey

Cited by 3 publications

References 55 publications

Patient satisfaction with the management of refractory and unexplained chronic cough in Canada: Results from a national survey

Patient satisfaction with the management of refractory and unexplained chronic cough in Canada: Results from a national survey

Wenn Husten zum langfristigen Problem wird

Current opinion in refractory and/or unexplained chronic cough

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