Burden of Heart Failure in Latin America: A Systematic Review and Meta-analysis

Ciapponi, Agustín; Alcaráz, Andrea; Calderón, María; Matta, María G.; Chaparro, Martin; Soto, Natalie; Bardach, Ariel

doi:10.1016/j.rec.2016.04.054

Cited by 55 publications

(57 citation statements)

References 42 publications

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“…4,18 In South America the HF prevalence is 1 % and in Australia it ranges between 1 % and 2 %, similar to Western countries (see Figure 2). 19,20 Although aetiologies and clinical characteristics have been studied in Sub-Saharan Africa, 21 there are actually no population studies providing insight into prevalence or incidence . are considered (see Figure 3).…”

Section: Prevalence and Incidencementioning

confidence: 99%

Global Public Health Burden of Heart Failure

Savarese

Lund

2017

Cardiac Failure Review

2,135

1,366

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EpidemiologyAccess at: www.CFRjournal.com Heart failure (HF) is a complex clinical syndrome characterised by the reduced ability of the heart to pump and/or fill with blood. In this review we describe the epidemiology of HF, providing data about the prevalence, incidence, mortality and morbidity worldwide. Prevalence and IncidenceCurrently 5.7 million people in the US have HF, but the projections are worrisome since it is expected that by 2030 more than 8 million people will have this condition, accounting for a 46 % increase in prevalence (see Figure 1). In Japan around 1 million people have the condition, accounting for 1 % of the population. [14][15][16] In India the estimates range between 1.3 and 4.6 million, which translates to a prevalence of 0.12-0.44 %, although this may be underestimated. 17 In Southeast Asia 9 million people have HF; with a prevalence of 6.7 % in Malaysia and 4.5 % in Singapore. 4,18 In South America the HF prevalence is 1 % and in Australia it ranges between 1 % and 2 %, similar to Western countries (see Figure 2). 19,20Although aetiologies and clinical characteristics have been studied in Sub-Saharan Africa, 21 there are actually no population studies providing insight into prevalence or incidence . AbstractHeart failure (HF) is a global pandemic affecting at least 26 million people worldwide and is increasing in prevalence. HF health expenditures are considerable and will increase dramatically with an ageing population. Despite the significant advances in therapies and prevention, mortality and morbidity are still high and quality of life poor. The prevalence, incidence, mortality and morbidity rates reported show geographic variations, depending on the different aetiologies and clinical characteristics observed among patients with HF. In this review we focus on the global epidemiology of HF, providing data about prevalence, incidence, mortality and morbidity worldwide.

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Section: Prevalence and Incidencementioning

confidence: 99%

Global Public Health Burden of Heart Failure

Savarese

Lund

2017

Cardiac Failure Review

2,135

1,366

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“…La letalidad intrahospitalaria global fue 9,2%. En Latinoamérica y Estados Unidos de Norteamérica, diversos estudios han reportado cifras de letalidad intrahospitalaria entre 3% y 17% 1,6 . En la región de las Américas se disponen de cifras en Brasil 24 , donde es cercana a 7%, y Argentina 25 , que muestra cifras que varían entre 4 y 12% según la localidad.…”

Section: Discussionunclassified

“…A pesar de los importantes avances en su diagnóstico y tratamiento, la mortalidad por IC sigue siendo elevada. La letalidad intrahospitalaria fluctúa entre 2% y 20% 4 , estimándose una cifra cercana a 11,5% en América Latina 5,6 , mientras que la sobrevida a cinco años es cercana a 50% una vez diagnosticada 7 . En relación a la evolución y pronóstico de la enfermedad se han descrito diferencias por sexo, por ejemplo, en Estados Unidos de Norteamérica 52,6% de los casos prevalentes y 52,2% de los casos incidentes corresponden a mujeres, además 51% de las hospitalizaciones y 57,8% de las muertes por IC ocurren en ellas 8 .…”

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Incidencia y letalidad intrahospitalaria por insuficiencia cardiaca en Chile: ¿Existen diferencias por sexo?

Díaz-Toro

Nazzal

2017

Rev. méd. Chile

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Incidence and hospital mortality due to heart failure. Are there any differences by sex?Background: Gender may influence the incidence, severity and hospital mortality due to heart failure (HF) (19.1 and 15.9% respectively, p < 0.01). Hospital mortality was also higher in women (9.7 and 8.6% respectively, p = 0.03). The factors associated with a higher hospital mortality were an age over 80 years (Odds Ratio (OR) 2.11; p < 0.01), a length of stay over seven days (OR 1.13; p = 0.04), being admitted to high complexity facilities (OR 1.29; p = 0.01) and being insured by the public national health fund (OR 1.94; p < 0.01). Conclusions: The incidence of hospital admissions due to HF is similar in men and women. There is high hospital mortality, especially in women. (Rev Med Chile 2017; 145: 703-709)

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“…Chronic Heart Failure (CHF) prevalence is over 5.8 million in the USA, and over 23 million worldwide 1 . In Latin America, estimated Heart Failure (HF) prevalence is 1% (95% CI, 0.1 to 2.7%) with 199 per 100,000 person-year 2 . The hospital readmission rates of patients with HF are 33%, 28%, 31%, and 35% at 3, 6, 12, and 24 to 60 months of follow-up (median duration of hospitalization of 7.0 days), with 1-year mortality rate of 24.5% (95% CI, 19.4 to 30.0%) and inhospital mortality of 11.7% (95% CI, 10.4 to 13.0%) 2 .…”

Section: Introductionmentioning

confidence: 99%

Psychometric properties of the Minnesota Living with Chronic Heart Failure Questionnaire in a Colombian population

Rojas

Hernández

Trujillo

et al. 2019

revsal

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Introduction: Although the Minnesota Living with Heart Failure Questionnaire (MLHF-Q) is one of the most widely used tools to assess Health-Related Quality of Life (HRQoL) in patients with chronic heart failure (CHF), it has not been validated in Latin American Spanish-speaking populations. Objective: We evaluated internal consistency and construct validity of the MLHF-Q in patients with CHF from Colombia. Methods: The Spanish version of the MLHF-Q was given to 200 patients. Cronbach's alpha was used to evaluate internal consistency. Confirmatory factorial Principal Component Analysis (PCA) and Rasch analysis were used to evaluate construct validity. The discriminative capacity was measured using the Mann-Whitney U test. Results: Median age was 64 years, 63% of the patients included in the study were men, and 79.5% had a left ventricular ejection fraction (LVEF) ≤ 45%. The median of the total score of HRQoL was 40 points (Q1=20; Q3=55), physical dimension 11 points (Q1=4; Q3=23) and emotional dimension 7 points (Q1=3; Q3=13). Global internal consistency of MLHF-Q was 0.91 (95% CI 0.89-0.93). In the PCA, the three dimensions explained 47.7% and 54.0% in Rasch analysis, in which five items presented misfit. Worse HRQoL was observed among women than men in the emotional dimension (p=0.047). Discriminative capacity for the overall score of the MLHF-Q and their subscales was observed in age and New York Heart Association (NYHA) functional class (p<0.05). Conclusions: Our findings confirmed the three-factor structure of the MLHF-Q, and satisfactory level for internal consistency. Additionally, these results suggest that the questionnaire adequately reflects the severity of the disease. However, further studies are required to validate these findings in Colombian population and to evaluate the sensitivity to change of the MLHF-Q in longitudinal designs.

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Burden of Heart Failure in Latin America: A Systematic Review and Meta-analysis

Cited by 55 publications

References 42 publications

Global Public Health Burden of Heart Failure

Global Public Health Burden of Heart Failure

Incidencia y letalidad intrahospitalaria por insuficiencia cardiaca en Chile: ¿Existen diferencias por sexo?

Psychometric properties of the Minnesota Living with Chronic Heart Failure Questionnaire in a Colombian population

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