Burden of lupus on work: Issues in the employment of individuals with lupus

Agarwal, Naveen; Kumar, Vinod

doi:10.3233/wor-162398

Cited by 15 publications

(12 citation statements)

References 37 publications

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“…Performance in these executive function domains is necessary for work productivity, particularly for jobs with a high cognitive requirement (38). This potential evidence of impairment may partially explain the substantial employment issues faced by SLE patients (39–41), although we did not detect any differences in cognitive performance by employment in this study. We found that, as expected, scores were not associated with age, sex, and race, given that the scores were adjusted for these characteristics.…”

Section: Discussioncontrasting

confidence: 61%

Geriatric Assessment of Physical and Cognitive Functioning in a Diverse Cohort of Systemic Lupus Erythematosus Patients: A Pilot Study

Plantinga

Tift

Dunlop-Thomas

et al. 2018

Arthritis Care & Research

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Section: Discussioncontrasting

confidence: 61%

Geriatric Assessment of Physical and Cognitive Functioning in a Diverse Cohort of Systemic Lupus Erythematosus Patients: A Pilot Study

Plantinga

Tift

Dunlop-Thomas

et al. 2018

Arthritis Care & Research

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“…This disease has significant adverse effects on many areas in life. The employment rate in patients with SLE is often affected by their disability and frequent sick leaves [11]. Authors Ekblom-Kullberg S. et al [12] also confirmed that sick leave and absence in work are two or three times more frequent in patients with SLE than in the healthy population.…”

Section: Discussionmentioning

confidence: 91%

Living with Systemic Lupus Erythematosus: A Profile of Young Female Patients

Macejová

Gecková

Husárová

et al. 2020

IJERPH

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The aim is to describe a profile of systemic lupus erythematosus (SLE) patient (socio-demographic data, course of disease, health status, and health care utilization, SLE impact on their life, SLE awareness) and to explore the association of patient’s perspective with clinical indicators. Adult patients diagnosed by SLE were recruited in outpatient clinics (n = 76, 88% female, data collected in 2012–2016, Slovakia). The association of patients’ perspective (SLE status, health complaints during remission, SLE impact, hospitalizations) with clinical activity (European Consensus Lupus Activity Measurement Index—ECLAM) and inflammatory marker (erythrocyte sedimentation rate—ESR) was assessed by t-test for independent variables and one-way ANOVA. Almost 17.9% of patients reported relapse. During remission, they mostly suffered fatigue and pain. Nearly all patients were on chronic pharmacological treatment. Most of the patients assessed SLE impact on their life as restrictive (56.9%) or very restrictive (23.1%). The most frequent source of information was their physician, and 67.2% reported that they have sufficient information about the disease and its treatment. Only the association of SLE status and hospitalization with clinical activity (ECLAM) and inflammatory marker (ESR) were confirmed. With recent improvements in diagnostics and therapy options, the prognosis for patients with SLE has improved. Nevertheless, the impact of this disease on all areas of a patient’s life is extensive.

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“…Fatigue can cause dramatic impairments in mood (14), diminish social aspects of life (15), lead to an inability to perform routine daily activities (16), and limit physical activity and work (17). Consequently, fatigue can severely affect well-being and has a financial burden on the individual, family, and society (18–21).…”

Section: Introductionmentioning

confidence: 99%

Fatigue, Sleep, and Autoimmune and Related Disorders

2019

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Profound and debilitating fatigue is the most common complaint reported among individuals with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 diabetes, celiac disease, chronic fatigue syndrome, and rheumatoid arthritis. Fatigue is multi-faceted and broadly defined, which makes understanding the cause of its manifestations especially difficult in conditions with diverse pathology including autoimmune diseases. In general, fatigue is defined by debilitating periods of exhaustion that interfere with normal activities. The severity and duration of fatigue episodes vary, but fatigue can cause difficulty for even simple tasks like climbing stairs or crossing the room. The exact mechanisms of fatigue are not well-understood, perhaps due to its broad definition. Nevertheless, physiological processes known to play a role in fatigue include oxygen/nutrient supply, metabolism, mood, motivation, and sleepiness—all which are affected by inflammation. Additionally, an important contributing element to fatigue is the central nervous system—a region impacted either directly or indirectly in numerous autoimmune and related disorders. This review describes how inflammation and the central nervous system contribute to fatigue and suggests potential mechanisms involved in fatigue that are likely exhibited in autoimmune and related diseases.

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Burden of lupus on work: Issues in the employment of individuals with lupus

Abstract: The paper presents innovative strategies that include early interventions and how employers andco-workers can provide helpful support that includes job accommodations to individuals with lupus.

Cited by 15 publications

References 37 publications

Geriatric Assessment of Physical and Cognitive Functioning in a Diverse Cohort of Systemic Lupus Erythematosus Patients: A Pilot Study

Geriatric Assessment of Physical and Cognitive Functioning in a Diverse Cohort of Systemic Lupus Erythematosus Patients: A Pilot Study

Living with Systemic Lupus Erythematosus: A Profile of Young Female Patients

Fatigue, Sleep, and Autoimmune and Related Disorders

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