2014
DOI: 10.1530/edm-14-0029
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Burkitt's lymphoma presenting with hypopituitarism: a case report and review of literature

Abstract: SummaryHypopituitarism is a rare presentation of Burkitt's lymphoma (BL). The purpose of this report is to present a case of BL presenting with panhypopituitarism and to review other case reports of lymphoma presenting with pituitary dysfunction to highlight the distinguishing features of these cases from other benign aetiologies of pituitary dysfunction such as non-functioning pituitary adenomas. We reviewed a total of 11 cases of lymphoma presenting with pituitary dysfunction published from 1998 to 2013 incl… Show more

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Cited by 5 publications
(9 citation statements)
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“…This was attributed to the posterior lobe circulation coming directly from the hypophyseal arteries, while the anterior lobe is nourished through the portal system [ 36 ]. However, in our case series and after literature review, we noticed that lymphoma may infiltrate more commonly the anterior (52%, n = 16) [ 7 , 9 , 12 , 13 , 16-20 , 22 , 23 , 25 , 26 , 30 , 32 , 33 ] rather than the posterior (26%, n = 8) [ 4 , 8 , 10 , 11 , 14 , 24 ] pituitary lobes. Interestingly, both lobes were affected in 22% of cases (n = 7) [ 6 , 18 , 20 , 27-29 , 31 ].…”
Section: Discussionmentioning
confidence: 59%
“…This was attributed to the posterior lobe circulation coming directly from the hypophyseal arteries, while the anterior lobe is nourished through the portal system [ 36 ]. However, in our case series and after literature review, we noticed that lymphoma may infiltrate more commonly the anterior (52%, n = 16) [ 7 , 9 , 12 , 13 , 16-20 , 22 , 23 , 25 , 26 , 30 , 32 , 33 ] rather than the posterior (26%, n = 8) [ 4 , 8 , 10 , 11 , 14 , 24 ] pituitary lobes. Interestingly, both lobes were affected in 22% of cases (n = 7) [ 6 , 18 , 20 , 27-29 , 31 ].…”
Section: Discussionmentioning
confidence: 59%
“…Hypofunction caused by similar related diseases has been reported, and supplementation with the appropriate hormones is sufficient. 14 , 15 …”
Section: Discussionmentioning
confidence: 99%
“… 7 Most patients exhibit pituitary dysfunction before systemic lymphoma becomes evident, however, in other cases, lymphoma can precede pituitary dysfunction or develop during the course of the disease, as was the case with our patient, whose pituitary symptoms were documented during hospitalization. 3 , 5 , 6 …”
Section: Discussionmentioning
confidence: 99%