Burn Hemangioma (BH) (Scalded Pyogenic Granuloma) versus Infantile Hemangioma: Report of Six Cases of BH and Its Effective Therapy with Oral Propranolol

Abstract

Infantile hemangioma and burn hemangioma have many similarities in clinical pictures, pathology and treatment. As infantile hemangioma appears usually after birth and then rapidly grow within few months and then a statue state and then involutes within few years while burn hemangioma so called burn pyogenic granuloma usually appears within days after burn with liquid and grow rapidly into many giant angiomatous masses and then after short time usually weeks or months will involute in more than 37.5% of cases.

Oral propranolol and topical timolol in the treatment of post‐burn pyogenic granuloma: Two cases and a review of the literature

“…Some studies have used oral and topical beta‐blockers such as propranolol, timolol, and betaxolol to treat PG, which are described in Table 1. In a study by Khalifa E et al, oral propranolol was used for 2 weeks to treat post‐burn pyogenic granulomas of two cases, which proved successful 13 …”

Burn Hemangioma: A New Variant of Hemangioma

“…The growth phases of both entities were similar with proliferative, statue, and spontaneous regression phases, in spite of the difference in time duration of these phases (Table 2). These great similarities make us to conclude that burn hemangioma should be considered as hemangioma rather than PG and deserve the name burn hemangioma, as was suggested previously by Professor Sharquie [19].…”

“…SPG have many clinical and histopathological similarities with infantile hemangioma in clinical imaging, course, and pathology [19].…”

“…Although burn-associated multiple PG or burn hemangioma was first described in 1978 with several similar reports, most of the published literature consist of single cases [4-14, 17, 18, 20-22]. Only two studies, Sharquie et al [19] (n = 6) and Zhao et al [15] (n = 15) have presented case series.…”

“…There are reported cases, mostly in children, of multiple eruptive hemangiomatous lesions following contact with boiling liquids [4‒25]. These lesions have been called scalded PG (SPG) and usually present as multiple eruptive nodules within days to weeks of scalding.…”