Burn Shock and Extravascular Sodium Deficiency—Treatment With Ringer's Solution With Lactate

Moyer, Carl A.; Margraf, Harry W.; Monafo, William W.

doi:10.1001/archsurg.1965.01320120001001

Cited by 117 publications

(21 citation statements)

References 13 publications

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“…1. Fluid resuscitation: Lactated ringer solution was used for the initial resuscitation, and the infusion rate was determined by the Parkland Formula (Moyer et al 1965) based on the extent of burn and body weight. Infants and young children received fluid with 5% dextrose at a maintenance rate in addition to the resuscitation fluid of Ringer's Lactate 3 -4 ml/kg/ %burn/day.…”

Section: Methodsmentioning

confidence: 99%

Differences in the Outcomes and Treatments of Extensively Burned Patients between a Chinese Hospital and a Japanese Hospital

Saitoh

Ben

Huan

et al. 2005

Tohoku J. Exp. Med.

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To know the therapeutic level at one's own institute is important and contributes to improving the treatment of patients. We compared the outcomes of extensively burned patients between a Chinese hospital and a Japanese hospital in order to identify the differences in the clinical treatment of severe burn patients. Thirty-four burn patients who were admitted to the National Defense Medical College Hospital (NDMC) in Japan and 95 burn patients who were admitted to the Changhai Hospital of the Second Military Medical University (SMMU) in China from January 1999 to December 2003 were studied. All patients were transported to the respective hospitals within 3 days after suffering burns and their total body surface area of burns was greater than 20%. Fourteen of the 34 patients (41.2%) at NDMC hospital and 1 of the 95 patients (1.1%) at SMMU hospital were injured by attempted suicide; namely, the suicide rate was significantly higher in the patients at NDMC hospital (p < 0.001). Moreover, the age (p = 0.005) and inhalation rate (p = 0.013) were significantly higher at NDMC hospital than those at SMMU hospital. Consequently, the survival rate at SMMU was higher than at NDMC in the patients with a burn surface area of greater than 80% or with a burn index of greater than 60. The excellent outcomes of the extensively burned patients at SMMU were in part due to the fact that Chinese doctors tend to perform an immediate tracheostomy and a traditional Chinese operation with alloskin, called microskin grafting or intermingled skin grafting.

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Section: Methodsmentioning

confidence: 99%

Differences in the Outcomes and Treatments of Extensively Burned Patients between a Chinese Hospital and a Japanese Hospital

Saitoh

Ben

Huan

et al. 2005

Tohoku J. Exp. Med.

View full text Add to dashboard Cite

show abstract

“…Moyer states [151] that in the recumbent patient, cardiac output declines significantly only when blood volume has decreased by some 30%. Cournand demonstrated [43] that during recovery from shock, right atrial pressure, systemic arterial pressure and cardiac output return to normal prior to the restoration of blood volume.…”

Section: Initial Intravascular Volume Effectmentioning

confidence: 99%

“…Recent research has shown that the therapeutic effects of volume substitution in shock is not a simple function of intravascular volume [50,51,146,147,150,151,192,193]. The needs of the whole extracellular space must obviously be considered.…”

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confidence: 99%

“…Furthermore, the studies of Moore, Moyer and Shires [50,51,146,147,150,151,192,193] and clinical experience show that the therapeutic effects of volume replacement in shock is not a simple function of intravascular volume. The whole extracellular compartment and the subtle balance between intravascular and interstitial space must obviously be con sidered.…”

mentioning

confidence: 99%

“…Conversely, Moore and his group have shown that endogenous volume restitution is accelerated by oral or parenteral administration of crystalloid solutions, the normal distribution ratio intravascular/ interstitial space being altered in favour of the vascular compartment in the posthemorrhagic state [146,147]. Moyer and his group find that the treatment of severe hemorrhage or bums with large amounts of Ringer's lactate only may produce the same therapeutic results as blood or colloids only [50,51,150,151]. In such situations, the extent and duration of the intravascular volume effect of the fluids administered appear to be of minor importance as compared to their effects on the whole extracellular space [190].…”

mentioning

confidence: 99%

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