Burns in Older Patients

Slater, H; Gaisford, John C.

doi:10.1111/j.1532-5415.1981.tb01231.x

Cited by 19 publications

(7 citation statements)

References 2 publications

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“…[15][16][17][18] Just as infants go through developmental phases in mastering locomotion and full use of all senses, older people develop a slow, subtle deterioration of their capacities, which may impede their ability to function but does not incapacitate them. 19 Several reports [20][21][22] have shown that at least 25% of patients who survive burn injury are able to maintain an independent lifestyle. This study has demonstrated that aggressive burn care results in a 72% survival rate (n = 159) in the older population.…”

Section: Commentmentioning

confidence: 99%

Outcome for Older Burn Patients

McGill

Kowal-Vern²,

Gamelli³

2000

Arch Surg

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Background: Physicians will be increasingly responsible for an aging society whose members demonstrate a notable striving for independence. Hypothesis: With standard treatment of burns, older patients will have a survival rate of more than 70%, with at least 60% of patients becoming fully functional 6 months after hospital discharge. Methods: A 7-year retrospective medical record review of burn unit patients was performed, and 221 (11%) of 1957 patients who were at least 59 years old were identified. Results: Of 97 women (44%) and 124 men (56%), 64 (29%) had an associated smoke inhalation injury; 146 (66%), flame injury; and 44 (20%), scald injury. The bedroom and/or living room were the most common areas of injury (90 [41%]), followed by outdoors and the workplace (62 [28%]), the kitchen (40 [18%]), the bathroom (18 [8%]), and the garage or basement (11 [5%]) (PϽ.005). One hundred twenty-six injuries (57%) were associated with impaired judgment, mobility, or both. On hospital admission, 74 patients (36%) were intubated,

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Section: Commentmentioning

confidence: 99%

Outcome for Older Burn Patients

McGill

Kowal-Vern²,

Gamelli³

2000

Arch Surg

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“…Other characteristics of the lung that make it one of the most susceptible organs to damage following injury include its delicate architecture and the presence of numerous alveolar macrophages that can independently respond to systemic cytokines [17,18]. The reasons why the lungs of aged individuals are even more susceptible to damage following injury than those of younger individuals, however, are not completely understood [4,19,20].…”

Section: Introductionmentioning

confidence: 99%

“…To date, most of the animal models that explore the mechanisms of pulmonary inflammation after injury use young adult animals [31][32][33][34]. Although many have shown that pulmonary sequelae have a higher incidence in elderly burn patients and are more detrimental, few have investigated the cause [2,4,19]. The main objective of this study was to examine pathologic differences in the lungs of young and aged animals in a murine model of burn injury and to determine whether the neutrophil chemokines, MIP-2 and KC, play a role in this process.…”

Section: Introductionmentioning

confidence: 99%

An age-associated increase in pulmonary inflammation after burn injury is abrogated by CXCR2 inhibition

Nomellini

Faunce

Gómez

et al. 2008

Journal of Leukocyte Biology

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Burn patients over the age of 60 are at a greater risk for developing pulmonary complications than younger patients. The mechanisms for this, however, have yet to be elucidated. The objective of this study was to determine whether increased chemoattraction plays a role in the age-related differences in pulmonary inflammation after burn injury. At 6 or 24 h after receiving sham or 15% total body surface area scald injury, lungs from young and aged mice were analyzed for leukocyte content by histological examination and immunostaining. Lungs were then homogenized, and levels of neutrophil chemokines, MIP-2 and KC, were measured. At 6 h after burn, the number of neutrophils was four times higher in the lungs of both burn groups compared with aged-matched controls (P<0.05), but no age difference was evident. At 24 h, in contrast, neutrophils returned to sham levels in the lungs of young, burn-injured mice (P<0.05) but did not change in the lungs of aged, burn-injured mice. Pulmonary levels of the neutrophil chemokine KC but not MIP-2 were consistently three times higher in aged, burn-injured mice compared with young, burn-injured mice at both time-points analyzed. Administration with anti-CXCR2 antibody completely abrogated the excessive pulmonary neutrophil content by 24 h (P<0.05), while not affecting the inflammatory response of the wounds. These studies show that CXCR2-mediated chemoattraction is involved in the pulmonary inflammatory response after burn and suggest that aged individuals sustaining a burn injury may benefit from treatment strategies that target neutrophil chemokines.

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“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] Various authors have identified issues surrounding hot tap water scalds, and reported on intervention programs aimed at reducing the incidence and severity of these scalds. [21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39] A crucial factor is the temperature of the water. Many researchers have suggested that this must be targeted in any serious attempt to reduce the incidence and severity of hot tap water scalds because it is more practical to modify than any other factor.…”

mentioning

confidence: 99%

Barriers to safe hot tap water: results from a national study of New Zealand plumbers

Jaye

Simpson²,

Langley³

2001

Inj Prev

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Introduction-Many countries still have unacceptably high hospitalizations and deaths from scalds from hot tap water. Prevention strategies implemented in some countries may not work in others. Legislation aimed at changing environments that are conducive to hot tap water scalds may not be eVective in many situations for a number of reasons, including lack of acceptability and practicality. Method-A qualitative study of a purposefully selected group of craftsman plumbers across New Zealand was conducted using a structured format with open ended questions. The questionnaire was administered by telephone. Information was sought on the opinions, knowledge, and practice of these plumbers regarding hot tap water safety in homes. Results-Several barriers to hot tap water safety in homes were identified by the plumbers. These included common characteristics of homes with unsafe hot tap water, such as hot water systems heated by solid fuel, and public ignorance of hot tap water safety. Other factors that emerged from the analysis included a lack of knowledge by plumbers of the hazards of hot tap water, as well as a lack of importance given to hot tap water safety in their plumbing practice. Shower performance and the threat to health posed by legionella were prioritized over the prevention of hot tap water scalds. Conclusion-The findings of this study allow an understanding of the practical barriers to safe hot tap water and the context in which interventions have been applied, often unsuccessfully. This study suggests that plumbers can represent a barrier if they lack knowledge, skills, or commitment to hot tap water safety. Conversely, they represent a potential source of advocacy and practical expertise if well informed, skilled, and committed to hot tap water safety. (Injury Prevention 2001;7:302-306)

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Burns in Older Patients

Cited by 19 publications

References 2 publications

Outcome for Older Burn Patients

Outcome for Older Burn Patients

An age-associated increase in pulmonary inflammation after burn injury is abrogated by CXCR2 inhibition

Barriers to safe hot tap water: results from a national study of New Zealand plumbers

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