Butadienyl Ketene: An Unexplored Intermediate in Organic Synthesis

Abstract

Butadienyl ketene is a useful intermediate for its role as 2- components in cycloaddition reactions with a variety of substrate such as simple/conjugated imines and dienes. The current review article summarizes the different reports on the in-situ generation of butadienyl ketene and their cycloaddition reactions to afford different heterocyclic systems. The chemistry of butadienyl ketene is explored only for their [2+2] and [4+2] cycloaddition with a variety of imines and azadiene such as 1,3-diazabuta-1,3-dienes for the synthesis of four- and six-membered heterocycles respectively.