Butanol production by Clostridium acetobutylicum in a continuous packed bed reactor

Napoli, Fabio Di; Olivieri, Giuseppe; Russo, Maria Elena; Marzocchella, Antonio

doi:10.1007/s10295-010-0707-8

Cited by 68 publications

(31 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Shamsudin et al 65 investigated the ABE production by Clostridium saccharoperbutylacetonicum N1-4 using different immobilization materials and concluded that the passive immobilization on polyurethane foam increased the production by 215.12%. Napoli et al 67 screened various carriers including silica gel, Tygon, Teflon, PVC and glass beads for better biofilm formation by observing SEM after 1 week.…”

Section: Immobilization Materials In Fermentationmentioning

confidence: 99%

Biobutanol: the outlook of an academic and industrialist

et al. 2013

View full text Add to dashboard Cite

The gradual shift of transportation fuels from oil based fuels to the alternative fuel resources and worldwide demand for energy has been the impetus for research to produce alcohol biofuels from renewable resources. Current bioethanol and biodiesel can, however, not cover an increasing demand for biofuels. Hence, there is an extensive need for advanced biofuels with superior fuel properties. The present review is focused on the developments of biobutanol, which is regarded to be superior to bioethanol in terms of energy density and hygroscopicity. Although acetone-butanolethanol (ABE) fermentation is one of the oldest large-scale fermentation processes, butanol yield by anaerobic fermentation remains sub-optimal. For sustainable industrial scale butanol production, a number of obstacles need to be addressed including choice of feedstock, low product yield, product toxicity to production strain, multiple end-products and downstream processing of alcohol mixtures.Metabolic engineering provides a means for fermentation improvements. Different strategies are employed in the metabolic engineering of Clostridia that aim to enhance the solvent production, improve selectivity for butanol production, and increase the tolerance of Clostridia to solvents. The introduction and expression of a non-clostridial butanol producing pathway in E. coli is most promising strategy for butanol biosynthesis. Several rigorous kinetic and physiological models for fermentation have been formulated, which form useful tool for optimization of the process. Due to the lower butanol titers in the fermentation broth, simultaneous fermentation and product removal techniques have been developed to improve production economics. With the use of new strains, inexpensive substrates, and superior reactor designs, economic ABE fermentation may further attract an attention of researchers all over the world. The present review is attempting to provide an overall outlook on discoveries and strategies that are being developed for commercial n-butanol production.

show abstract

Section: Immobilization Materials In Fermentationmentioning

confidence: 99%

Biobutanol: the outlook of an academic and industrialist

et al. 2013

View full text Add to dashboard Cite

show abstract

“…ABE fermentation in any regime can be combined with cells immobilization performed by different methods -entrapment in alginate (Largier et al, 1985), use of membrane bioreactor (Pierrot et al, 1986) or cells adsorption on porous material (S.Y. Napoli et al, 2010). Recently, final report of the US DOE grant (Ramey & Yang, 2004) has revealed a novel approach toward ABE fermentation.…”

Section: Novel Approaches Toward Biobutanol Productionmentioning

confidence: 99%

Perspectives of Biobutanol Production and Use

Patáková¹,

Maxa²,

Rychtera³

et al. 2011

Biofuel's Engineering Process Technology

View full text Add to dashboard Cite

“…Estes produtos são butanol (principal), etanol e acetona (fermentação ABE) presente em diferentes títulos dependendo da cepa utilizada (Napoli et al, 2010). Atualmente esta determinação é feita utilizando a cromatografia gasosa (Liu et al, 2010;Lépiz-Aguilar et al, 2011) na maior parte dos estudos.…”

Section: Introductionunclassified

Desenvolvimento De Uma Metodologia Rápida E De Baixo Custo Para Quantificação De Acetona-Butanol-Etanol Em Processos Fermentativos Industriais

Visioli¹,

Alves²,

Trindade³

et al. 2015

Anais Do XX Congresso Brasileiro De Engenharia Química

View full text Add to dashboard Cite

RESUMO -Biobutanol obtido por fermentação clostridial representa um importante biocombustível. Neste cenário, desenvolveu-se um método baseado na densidade da mistura para determinação da concentração dos solventes acetona, butanol e etanol (ABE) como alternativa ao uso de métodos baseados em cromatografia. Para esta proposta, diversos pontos de calibração foram preparados usando diferentes meios de cultura para representar condições reais para a fermentação clostridial. As densidades das misturas foram determinadas para concentrações de ABE variando entre 0 e 25 g/L, em três diferentes níveis de concentração de açúcar para representar a evolução do meio durante a fermentação. Os resultados obtidos demonstram uma relação linear da variação da densidade com as concentrações de ABE e açúcares. A principal contribuição deste trabalho foi a determinação da concentração dos solventes ABE com uma metodologia simples, rápida e de baixo custo.

show abstract

Butanol production by Clostridium acetobutylicum in a continuous packed bed reactor

Cited by 68 publications

References 22 publications

Biobutanol: the outlook of an academic and industrialist

Biobutanol: the outlook of an academic and industrialist

Perspectives of Biobutanol Production and Use

Desenvolvimento De Uma Metodologia Rápida E De Baixo Custo Para Quantificação De Acetona-Butanol-Etanol Em Processos Fermentativos Industriais

Contact Info

Product

Resources

About