Butyrate-induced IL-22 expression in fish macrophages contributes to bacterial clearance

Identification and Characterization of a Potential Probiotic, Clostridium butyricum G13, Isolated from the Intestine of the Mud Crab (Scylla paramamosain)

“…Recently, probiotics that produce butyrate have been widely used in aquaculture ( 36 ). Microbial community composition and metabolism are significantly related to the content and composition of SCFAs in the intestine, especially butyric acid ( 37 – 39 ). C. butyricum produces butyric acid, which can improve the balance of the host intestinal flora and reduce the probability of intestinal infection with pathogenic bacteria ( 40 ).…”