Buyang Huanwu decoction ameliorates coronary heart disease with Qi deficiency and blood stasis syndrome by reducing CRP and CD40 in rats

Neuroprotective effects of Buyang Huanwu decoction against hydrogen peroxide induced oxidative injury in Schwann cells

“…A lot of previous studies have discussed the effectiveness of BYHWD in promoting blood circulation and amelioration of coronary heart disease (Zhang et al, 2010). It has been also reported that BYHWD improves the motor function and reduces spinal damage (Wang and Jiang, 2009).…”

“…Buyang Huanwu decoction (BYHWD) is a well known Chinese herbal medicine, used widely in the treatment of cerebrovascular diseases for centuries (Zhang et al, 2010). Previous study has also demonstrated that BYHWD promotes nerve regeneration .…”

An integrative approach of linking traditional Chinese medicine pattern classification and biomedicine diagnosis

“…The changes in peripheral IgA level and platelet number positively correlated with the grade of cartilage damage in active RA patients, thus supporting the hypothesis (Zha et al, 2006;He et al, 2007b). In the clinical practice, the CMMs with activating blood stasis pattern, and those reinforcing deficiency pattern and containing polysacharides or animal proteins were used for the treatment (Yang et al, 2003;Zhang et al, 2010).…”

The effects of Buyang Huanwu Decoction on hemorheological disorders and energy metabolism in rats with coronary heart disease

“…Lyophilization was conducted and the 45 g lyophilized powder was re-dissolved in distilled water to a final concentration of 3 g/ml (equivalent to the overall dry weight of the crude drugs). Tongxinluo capsule (TXL) has been used to treat CHD with qi deficiency and blood stasis syndrome in clinic by replenishing qi, removing stasis and dredging collateral and TXL was used here as a positive control drug (Zhang et al, 2010).…”

“…Considerable clinical evidence has implicated that BYHWD can be used for the treatment of coronary heart disease (CHD) with qi deficiency and blood stasis syndrome and improve the patients' quality of life (Zhou and Deng, 2002;Cai et al, 2004). Our previous study has found that the ameliorative effects of BYHWD on CHD rats with qi deficiency and blood stasis syndrome are associated with the inhibition of C-reactive protein and cluster of differentiation 40 (CD40) and the regulation of endotheliumderived vasoactive factors (Zhang et al, 2010). In addition, clinical and epidemiological studies have suggested that hemorheological disorders play an important role in the pathogenesis and development of CHD (Koenig and Ernst, 1992).…”