C-Arm CT for Assessing Initial Failure of Iodized Oil Accumulation in Chemoembolization of Hepatocellular Carcinoma

Iwazawa, Jin; Ohue, Shoichi; Kitayama, Toyoki; Sassa, Seitaro; Mitani, T.

doi:10.2214/ajr.10.5614

Cited by 27 publications

(21 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The role of CBCT can also be seen in therapy response assessment, in particular for Lipiodol deposition (Fig. 4) [27, 38-41] or for marginal contrast retention with DEB, which is associated with successful treatment outcomes 1 month post-DEB [27]. …”

Section: Clinical Applicationsmentioning

confidence: 99%

C-arm cone-beam computed tomography in interventional oncology: technical aspects and clinical applications

et al. 2014

View full text Add to dashboard Cite

C-arm cone-beam computed tomography (CBCT) is a new imaging technology integrated in modern angiographic systems. Due to its ability to obtain cross-sectional imaging and the possibility to use dedicated planning and navigation software, it provides an informed platform for interventional oncology procedures. In this paper, we highlight the technical aspects and clinical applications of CBCT imaging and navigation in the most common loco-regional oncological treatments.

show abstract

Section: Clinical Applicationsmentioning

confidence: 99%

C-arm cone-beam computed tomography in interventional oncology: technical aspects and clinical applications

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Incomplete tumor treatment negatively impacts survival (91,92). The imaging characteristics of different chemoembolic agents differ substantially, thus requiring different posttreatment CBCT techniques.…”

Section: Cbct To “Assess” Treatment Success: Rationale and Techniquesmentioning

confidence: 99%

“…Lipiodol is a radiopaque contrast agent, which has also been used as a biomarker for HCC (93). Lipiodol deposition in the tumor is a prognostic factor affecting local recurrence of HCC and may be determined directly during the procedure using unenhanced CBCT, which offers equivalent lipiodol detection accuracy to unenhanced MDCT imaging (91,92,94–96). Drug-eluting beads, commonly loaded with doxorubicin (adriamycin), are radiolucent and so are mixed with contrast agent during delivery.…”

Section: Cbct To “Assess” Treatment Success: Rationale and Techniquesmentioning

confidence: 99%

How I Do It: Cone-Beam CT during Transarterial Chemoembolization for Liver Cancer

Tacher¹,

Radaelli²,

Lin³

et al. 2015

Radiology

152

119

View full text Add to dashboard Cite

Cone-beam computed tomography (CBCT) is an imaging technique that provides computed tomographic (CT) images from a rotational scan acquired with a C-arm equipped with a flat panel detector. Utilizing CBCT images during interventional procedures bridges the gap between the world of diagnostic imaging (typically three-dimensional imaging but performed separately from the procedure) and that of interventional radiology (typically two-dimensional imaging). CBCT is capable of providing more information than standard two-dimensional angiography in localizing and/or visualizing liver tumors (“seeing” the tumor) and targeting tumors though precise microcatheter placement in close proximity to the tumors (“reaching” the tumor). It can also be useful in evaluating treatment success at the time of procedure (“assessing” treatment success). CBCT technology is rapidly evolving along with the development of various contrast material injection protocols and multiphasic CBCT techniques. The purpose of this article is to provide a review of the principles of CBCT imaging, including purpose and clinical evidence of the different techniques, and to introduce a decision-making algorithm as a guide for the routine utilization of CBCT during transarterial chemoembolization of liver cancer.

show abstract

“…For example, Lipiodol®/Lipiodol UltraFluide®, a liquid embolic agent, has been widely used as drugcarrying and blood-vessel-embolic materials in TACE since they could selectively accumulate in intratumoral peripheral vessels [13]. However, many studies indicated Lipiodol had poor properties in drugcontrolled release [14,15], and it was difficult for Lipiodol to achieve long-term embolism due to in vivo rapid elimination [16]. Ivalon® (PVA foam embolization particles), on the other hand, was difficult to flow into peripheral arteries in tumor due to its large size (180-300 μm), but showed excellent long-term embolism in TACE [17].…”

Section: Introductionmentioning

confidence: 99%

The studies about doxorubicin-loaded p(N-isopropyl-acrylamide-co-butyl methylacrylate) temperature-sensitive nanogel dispersions on the application in TACE therapies for rabbit VX2 liver tumor

Qian

Wan

et al. 2015

Journal of Controlled Release

View full text Add to dashboard Cite

C-Arm CT for Assessing Initial Failure of Iodized Oil Accumulation in Chemoembolization of Hepatocellular Carcinoma

Abstract: C-arm CT is nearly equivalent to MDCT for detecting incomplete iodized oil accumulation after TACE, suggesting that the immediate assessment of iodized oil accumulation with C-arm CT without the need to perform follow-up unenhanced MDCT is likely feasible.

Cited by 27 publications

References 22 publications

C-arm cone-beam computed tomography in interventional oncology: technical aspects and clinical applications

C-arm cone-beam computed tomography in interventional oncology: technical aspects and clinical applications

How I Do It: Cone-Beam CT during Transarterial Chemoembolization for Liver Cancer

The studies about doxorubicin-loaded p(N-isopropyl-acrylamide-co-butyl methylacrylate) temperature-sensitive nanogel dispersions on the application in TACE therapies for rabbit VX2 liver tumor

Contact Info

Product

Resources

About