2015
DOI: 10.1159/000430094
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C-Peptide and 24-Hour Urinary C-Peptide as Markers to Help Classify Types of Childhood Diabetes

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Cited by 7 publications
(2 citation statements)
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“…Those conditions were considered for C-peptide quantification in our protocol. Regarding the different assays for its determination, C-peptide could also be quantified after 8 to 10 h of fasting or after stimulation with glucagon, intravenous/oral glucose, tolbutamide, sulfonylurea, or a mixed meal [26], but these techniques are not effective in the presence of insulin treatment. Despite the fact that fasting C-peptide has been criticized due to its limited ability to detect subtle levels, other studies have proven that it correlates with urinary C-peptide [26].…”
Section: Discussionmentioning
confidence: 99%
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“…Those conditions were considered for C-peptide quantification in our protocol. Regarding the different assays for its determination, C-peptide could also be quantified after 8 to 10 h of fasting or after stimulation with glucagon, intravenous/oral glucose, tolbutamide, sulfonylurea, or a mixed meal [26], but these techniques are not effective in the presence of insulin treatment. Despite the fact that fasting C-peptide has been criticized due to its limited ability to detect subtle levels, other studies have proven that it correlates with urinary C-peptide [26].…”
Section: Discussionmentioning
confidence: 99%
“…Regarding the different assays for its determination, C-peptide could also be quantified after 8 to 10 h of fasting or after stimulation with glucagon, intravenous/oral glucose, tolbutamide, sulfonylurea, or a mixed meal [26], but these techniques are not effective in the presence of insulin treatment. Despite the fact that fasting C-peptide has been criticized due to its limited ability to detect subtle levels, other studies have proven that it correlates with urinary C-peptide [26]. Urinary C-peptide levels had a high sensitivity for differentiating MODY from T1D or T2D [27], but had the disadvantage of being useful only in patients with adequate renal function.…”
Section: Discussionmentioning
confidence: 99%