2019
DOI: 10.1016/j.urolonc.2019.04.002
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C-reactive protein-albumin ratio as a prognostic factor in renal cell carcinoma – A data from multi-institutional study in Japan

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Cited by 37 publications
(26 citation statements)
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“…Several inflammatory markers, such as modified Glasgow Prognostic Score (mGPS), C-reactive protein (CRP), and the combination of neutrophil, lymphocyte, monocyte count plays a key role in prognosis in RCC [57]. Recently, the C-reactive protein to albumin ratio (CAR) as a novel inflammation-based prognostic score, combination of CRP and albumin, has shown significant prognostic value in RCC [810]. However, most of these studies include only small study populations and their conclusions remain inconclusive [11, 12].…”
Section: Introductionmentioning
confidence: 99%
“…Several inflammatory markers, such as modified Glasgow Prognostic Score (mGPS), C-reactive protein (CRP), and the combination of neutrophil, lymphocyte, monocyte count plays a key role in prognosis in RCC [57]. Recently, the C-reactive protein to albumin ratio (CAR) as a novel inflammation-based prognostic score, combination of CRP and albumin, has shown significant prognostic value in RCC [810]. However, most of these studies include only small study populations and their conclusions remain inconclusive [11, 12].…”
Section: Introductionmentioning
confidence: 99%
“…Firstly, the patient selection was biased as the cohort in the study was retrospectively designed. Secondly, we could not assess potential prognostic factors, such as smoking, molecular markers, and peripheral blood measurement at surgery [29][30][31]. Nevertheless, our findings collected from multi-institutional Japanese data set further confirmed the improved survival in patients with higher BMI compared to lower BMI for non-metastatic RCC treated with nephrectomy, and intriguingly, this finding was restricted to male, but not to female.…”
Section: Discussionmentioning
confidence: 71%
“…Firstly, the patient selection was biased as the cohort in the study was retrospectively designed. Secondly, we could not assess potential prognostic factors, such as smoking, molecular markers, and peripheral blood measurement at surgery [33][34][35]. In particular, smoking is a well-accepted risk factor for RCC development regardless of sex [36].…”
Section: Discussionmentioning
confidence: 99%