C-reactive Protein Associates with Metabolic Syndrome: An Improved Conventional Assay may Fit for Purpose in Population-based Analyses

Abstract

improved conventional CRP assays allow the measurement of 1 mg/L with CV <10% [7,10], and also show good concordance with hs-CRP data for the range near 1 mg/L [7]. Given these considerations, we analyzed the health checkup data involving the CRP values obtained by an improved conventional method and examined their associations with the MetS-related parameters. MethodsWe used a dataset derived from the health screening program performed by the Yuport Medical Checkup Center in Tokyo from April 1998 to 2006. The details of this program have been reported elsewhere [11,12]. For repeat participants, first-visit data was used for the study. After the exclusion of 1,230 subjects with medical history and 594 subjects with