C-reactive protein postoperative values to predict clinically relevant postoperative pancreatic fistula after distal pancreatectomy

Abstract

IntroductionDespite significant medical and technological advances, the incidence of Postoperative pancreatic fistula (POPF) after distal pancreatectomy (DP) is reported to be between 3-45%. The main objective of our study was to analyse the early post-surgical risk factors for developing POPF after DP. Material and methodsA retrospective observational study was conducted on a prospective basis of patients undergoing PD in a tertiary hospital from January 2011 to December 2021. Sociodemographic, preoperative analytical, tumour-related and postoperative complications variables were analysed. ResultsOf the 52 patients analysed, 71.8% of the sample had postoperative drains amylase elevation; however, 25.7% of the total had Grade-B and/or Grade-C POPF. Univariate logistic regression with the variables studied showed the following as risk factors for B-C o clinically relevant POPF: amylase values in drainage at 5 th POD [p=0.

Preoperative anaemia in distal pancreatectomy: a propensity-score matched analysis

“…In our results, we found a significantly increased CRP in patients with anaemia. However, some authors found this condition to be often associated with postoperative inflammatory complications; the relation to anaemia is currently not clear enough [ 39 , 40 ]. Preoperative anaemia workup must be standard before distal pancreatectomy.…”