C₆₀‐assisted laser desorption/ionization mass spectrometry in the analysis of phosphotungstic acid

Abstract

An application of C@-assisted laser desorptionhonization mass spectrometry to a heteropoly inorganic system: phosphotungstic acid, HQO,(WO,),,, is presented. A nitrogen laser (337 nm) on a linear tandem time-of-flight mass spectrometer is used for the observation of the laser-power dependence of mass spectra of this material.

Recent progress in application of carbon nanomaterials in laser desorption/ionization mass spectrometry

“…Bare fullerenes The Willett group reported the first example of use of fullerene as a MALDI matrix in 1994 [22,23]. Proteins such as cytochrome c (12 kDa) and bovine albumin (66 kDa) could been successfully analyzed with the method, but it suffered from low sensitivity and narrow detectable mass range as a result of poor dispersion of polar analytes in the nonpolar fullerene.…”

Nanostructured Affinity Surfaces for MALDI‐TOF‐MS–Based Protein Profiling and Biomarker Discovery

“…They have a strong role in the recent past in certain biological applications coupled to desorption/ionization. The sample supports for use in matrix-free LDI-MS are graphite [27], carbonnanotubes [28], fullerenes [29] or amorphous carbon [30]. The graphite powder is reported to be packed in GELoader tips for desalting and concentration of peptide mixtures prior to LDI-MS [31].…”

Hydrogen Radical Removal Causes Complex Overlapping Isotope Patterns of Aromatic Carboxylic Acids in Negative-ion Matrix-assisted Laser Desorption/Ionization Mass Spectrometry

“…e compounds themselves are easily ionized with laser irradiation. [1][2][3][4] In negative-ion MALDI-MS, for instance, the negative molecular ion M − of fullerene and anthracene,…”