C0143: Holter 24-Hours ECG and Clinical Predictors for Arrhythmia Detection in Patients with Cardioembolic Stroke Profile

Rodriguez-Leal, C.; Toro, Rocío; Feijoo, Margarita; Cabeza-Letrán, Luisa

doi:10.1016/s0049-3848(14)50362-3

Cited by 1 publication

(2 citation statements)

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“…Twenty-four articles, 16 full manuscripts and 8 abstracts, of 1205 identified citations fulfilled the eligibility criteria (Figure 1). 3,15–37 Three studies (13%) were randomized controlled trials and 21 (87%) were prospective observational (online supplementary Table 2). After seven studies were excluded from the analysis because of missing data, 17 studies were included in the meta-analysis.…”

Section: Resultsmentioning

confidence: 99%

“…32 We excluded 147 patients because in 17 cases AF was detected at presentation, 27,37 and for 130 patients the detection rate was not available. 15,18,25,30,34–36 Thus, a total of 1163 patients from 17 studies were eligible for analysis (supplementary Table 2). Since seven of these studies investigated more than one modality in the same study cohort, the number of included study subgroups exceeded the number of eligible studies.…”

Section: Resultsmentioning

confidence: 99%

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Cardiac monitoring for detection of atrial fibrillation after TIA: A systematic review and meta-analysis

Korompoki

Giudice

Hillmann

et al. 2016

International Journal of Stroke

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Background and purpose The detection rate of atrial fibrillation has not been studied specifically in transient ischemic attack (TIA) patients although extrapolation from ischemic stroke may be inadequate. We conducted a systematic review and meta-analysis to determine the rate of newly diagnosed atrial fibrillation using different methods of ECG monitoring in TIA. Methods A comprehensive literature search was performed following a pre-specified protocol the PRISMA statement. Prospective observational studies and randomized controlled trials were considered that included TIA patients who underwent cardiac monitoring for >12 h. Primary outcome was frequency of detection of atrial fibrillation ≥30 s. Analyses of subgroups and of duration and type of monitoring were performed. Results Seventeen studies enrolling 1163 patients were included. The pooled atrial fibrillation detection rate for all methods was 4% (95% CI: 2-7%). Yield of monitoring was higher in selected (higher age, more extensive testing for arrhythmias before enrolment, or presumed cardioembolic/cryptogenic cause) than in unselected cohorts (7% vs 3%). Pooled mean atrial fibrillation detection rates rose with duration of monitoring: 4% (24 h), 5% (24 h to 7 days) and 6% (>7 days), respectively. Yield of non-invasive was significantly lower than that of invasive monitoring (4% vs. 11%). Significant heterogeneity was observed among studies (I=60.61%). Conclusion This first meta-analysis of atrial fibrillation detection in TIA patients finds a lower atrial fibrillation detection rate in TIA than reported for IS and TIA cohorts in previous meta-analyses. Prospective studies are needed to determine actual prevalence of atrial fibrillation and optimal diagnostic procedure for atrial fibrillation detection in TIA.

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