C3AR1 promotes ovarian cancer progression and induces suppressive immunocyte infiltration: evidence from comprehensive bioinformatics analysis and experiments
Abstract:Background
C3AR1 was reported in driving tumor immunity in multiple cancers. However, its roles in ovarian cancer remain unclear. This study aims to determine role of C3AR1 in prognosis and regulating tumor infiltrating immune cells of ovarian cancer (OC).
Material and Methods
The expression, prognosis and clinical data related to C3AR1 were collected from public databases such as The Cancer Genome Atlas (TCGA), Human Protein Atlas (HPA) and Clinical Proteomics Tumor Analysis Alliance (CPTAC), and further an… Show more
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