C4-Sulfenylation of 4-iodine-1H-pyrazole-5-amine with arylsulfonyl hydrazide in water

Iodophor-Catalyzed Disulfenylation of Amino Naphthalenes with Aryl Sulfonyl Hydrazines

“…Considering that povidone iodine as a commercially readily available reagent has the advantage of possessing a two-component reagent (iodine and polyvinylpyrrolidone surfactant), this provides a rare opportunity for iodine-catalyzed organic reactions in the aqueous phase. On the basis of our previous research work [ 19 , 20 , 21 , 22 ], we herein report the iodophor-catalyzed disulfenylation of naphthylamine with aryl sulfonyl hydrazines; a series of 1,3-bis(arylthio)naphthalene-2-amines and 2,4-bis(arylthio)naphthalene-1-amines were obtained in moderate to excellent yields ( Scheme 1 c).…”

One-pot synthesis of 11-sulfenyl dibenzodiazepinesviatandem sulfenylation/cyclization ofo-isocyanodiaryl amines and diaryl disulfides

“…as well as organic sulfur reagents (thiols, 7b,15 KSAc, 16 N-thioarylphthalimides, 17 arylsulfonyl chlorides, 18 sulfonyl hydrazides, 19 thioesters, 20 sulfinates 21 and disulfides 4d,e,22-25 ).…”

“…Varying the reaction temperature did not lead to posi-tive results (Table 1, entries [16][17][18]. No improvement was achieved when solvents such as 1,4-dioxane, dichloroethane (DCE), N-methylpyrrolidone (NMP), tetrahydrofuran (THF), acetonitrile (MeCN), and methanol (MeOH) were screened (Table 1, entries [19][20][21][22][23][24]. The results showed that the reaction did not proceed smoothly under a nitrogen or oxygen atmosphere (Table 1, entries 25 and 26).…”