Ca19Zn2(PO4)14 Nanoparticles: Synthesis, characterization and its effect on the colonization of Streptococcus mutans on tooth surface

Shakerimoghaddam, Ali; Safardoust-Hojaghan, Hossein; Amiri, Omid; Salavati‐Niasari, Masoud; Kazemi, Ahmad; Khaledi, Azad

doi:10.1016/j.molliq.2022.118507

Cited by 5 publications

(2 citation statements)

References 43 publications

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“…Among the studied NPs, the authors found a high activity for ZnO NPs; however, the Ca 19 Zn 2 (PO 4 ) 14 NPs exhibited half of the MIC value found for ZnO NPs. Thus, the authors presented the possibility of coating dental surfaces [ 120 ].…”

Section: Drug Delivery Systems Used In the Prevention And Treatment O...mentioning

confidence: 99%

New Technological Approaches for Dental Caries Treatment: From Liquid Crystalline Systems to Nanocarriers

et al. 2023

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Dental caries is the most common oral disease, with high prevalence rates in adolescents and low-income and lower-middle-income countries. This disease originates from acid production by bacteria, leading to demineralization of the dental enamel and the formation of cavities. The treatment of caries remains a global challenge and the development of effective drug delivery systems is a potential strategy. In this context, different drug delivery systems have been investigated to remove oral biofilms and remineralize dental enamel. For a successful application of these systems, it is necessary that they remain adhered to the surfaces of the teeth to allow enough time for the removal of biofilms and enamel remineralization, thus, the use of mucoadhesive systems is highly encouraged. Among the systems used for this purpose, liquid crystalline systems, polymer-based nanoparticles, lipid-based nanoparticles, and inorganic nanoparticles have demonstrated great potential for preventing and treating dental caries through their own antimicrobial and remineralization properties or through delivering drugs. Therefore, the present review addresses the main drug delivery systems investigated in the treatment and prevention of dental caries.

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Section: Drug Delivery Systems Used In the Prevention And Treatment O...mentioning

confidence: 99%

New Technological Approaches for Dental Caries Treatment: From Liquid Crystalline Systems to Nanocarriers

et al. 2023

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“…Adversely, the combination of zinc oxide nanoparticles (ZnO NPs) with hydroxyapatite nanoparticles (HAP NPs) to create Zn-substituted hydroxyapatite nanoparticles (Ca19Zn2(PO4)14 NPs) focuses on targeting bacteria through depressing the FTF (8.15 times) and GFT (8.42 times) genes' expression. Results show significant impact on S. mutans growth and biofilm formation as well as bacterial adherence, which makes them applicable as dental coatings [56].…”

Section: Decreasing Expression Of Ftf and Gft Genes In S Mutansmentioning

confidence: 99%

Nanoparticles in Dentistry—Current Literature Review

et al. 2023

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Interest in the topic of nanoparticles (NPs) and nanomaterials used in dentistry is growing in research as well as clinical settings. In recent years, an increasing number of nanomaterials have been developed and tested, enabling novel solutions unavailable in dentistry before. The aim of the article is to review the current status of knowledge regarding NPs used in modern dentistry. The analysis was made using Science Direct, PubMed and Scopus databases, and articles were selected based on relevance and topicality. The exclusion criteria determining timeliness consisted of a selection of essential works on this topic no older than 2017. Regarding appropriateness, only studies on nanoparticles in the field of dentistry were considered, and were categorized into three subtopics: antimicrobial NPs, therapeutic NPs, material property improving NPs. Each category was further divided into specific groups focusing on the clinical use of the particles. Inside every section, analysis concerning the current state of knowledge about the use and properties of nanoparticles within specific material groups was conducted. Additionally, within this article, common and rising trends in the NPs field were analyzed; additionally, based on novel NPs approaches, possible future applications and dangers were considered.

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Advancing oral health: the antimicrobial power of inorganic nanoparticles

Kim,

Lee

et al. 2024

J. Korean Ceram. Soc.

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Ca19Zn2(PO4)14 Nanoparticles: Synthesis, characterization and its effect on the colonization of Streptococcus mutans on tooth surface

Cited by 5 publications

References 43 publications

New Technological Approaches for Dental Caries Treatment: From Liquid Crystalline Systems to Nanocarriers

New Technological Approaches for Dental Caries Treatment: From Liquid Crystalline Systems to Nanocarriers

Nanoparticles in Dentistry—Current Literature Review

Advancing oral health: the antimicrobial power of inorganic nanoparticles

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