2024
DOI: 10.24272/j.issn.2095-8137.2023.373
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Cadherin-18 loss in prospermatogonia and spermatogonial stem cells enhances cell adhesion through a compensatory mechanism

Xiao-Xiao Li,
Dan-Chen Zhang,
Yan Wang
et al.

Abstract: Extracellular membrane proteins play key roles in the interaction of testicular microenvironment germline stem cell (GSC) through mediating cell attachment, recognition, and signal transduction processes. Cadherin 18 (CDH18), a type II classical cadherin, is mainly expressed in the nervous and reproductive systems. Here we report the expression of CDH18 in the Prospermatogonia (ProSGs) of neonatal pigs and mouse spermatogonial stem cells (SSCs). Disruption of CDH18 expression showed no detrimental impact on ce… Show more

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