Cadmium-113 Fourier transform nuclear magnetic resonance of cadmium(II) carbonic anhydrases and cadmium(II) alkaline phosphatase

Armitage, Ian M.; Pajer, Raymond T.; Uiterkamp, A.J.M. Schoot; Chlebowski, J F; Coleman, Joseph E.

doi:10.1021/ja00434a058

Cited by 79 publications

(32 citation statements)

References 5 publications

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“…In a first approximation this displacement may be assumed to be linear so that eq. [6] is obtained from eq. [4].…”

Section: Resultsmentioning

confidence: 99%

“…The consequence of this is that in the transition region there will in general be more ions in site I than predicted by eq. [6]. In the future systems may be found where the opposite is true, this is to say that ions will move into site I1 faster than predicted by eq.…”

mentioning

confidence: 94%

“…The binding of ions to the polar groups of amphiphilic compounds is a subject of continuing interest and of great importance in various areas of chemistry and biochemistry (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12). Unfortunately, as is often the case with biological systems, studies are hampered by the extreme complexity of the system being studied.…”

Section: Introductionmentioning

confidence: 99%

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The interactions of the chloride and bromide ions in nematic lyotropic liquid crystalline solution

Tracey¹

1984

Can. J. Chem.

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ALAN S . TRACEY. Can. J. Chem. 62, 2161Chem. 62, (1984.The binding interactions of chloride and bromide ions have been studied in nematic lyotropic liquid crystalline materials prepared using the mixed detergent system of potassium dodecanoate/dodecylpyridinium chloride. The results from this study show that a three-site model of binding is sufficient to describe the behaviour of the observed quadrupole splittings. The results clearly reveal that the selectivity of ion binding is a function not only of the counterion but also of the detergent ion to which it is bound. In the cationic mesophase prepared from decylpyridinium, Cl-binds simultaneously to two and Br-to three headgroups. This contrasts with the alkyltrimethylammonium bromide system, where Cl-binds to three cationic amphiphiles while Br-binds to two. Sodium ion appears indifferent to the type of cationic detergent present, a result in accordance with the expectation that its binding is determined only by the headgroup of the anionic detergent. Extension of the three-site theory to take into account the effect of surface charge on ion binding provides information concerning relative strengths of binding. In the dodecylpyridinium system CI-binds only weakly compared to Br-whereas in the alkyltrimethylammonium system Clbinds more strongly than Br-. K' binds most strongly to dodecanoate anion, CsC least strongly, and the other alkali metal ions occupy intermediate positions. IntroductionThe binding of ions to the polar groups of amphiphilic compounds is a subject of continuing interest and of great importance in various areas of chemistry and biochemistry (1-12). Unfortunately, as is often the case with biological systems, studies are hampered by the extreme complexity of the system being studied. For the particular case of ion binding a further impediment often encountered is that the details of the stereochemical requirements which are imposed on a substrate by the ion during binding interactions are not known. A study of simple systems can often provide the background information necessary for understanding the more complex systems.A particularly suitable medium for studying ion interactions is that of lyotropic liquid crystals. Of these materials, those which have the property of spontaneously aligning in the magnetic field of a nuclear magnetic resonance spectrometer provide distinct advantages, the most important one being "sharp" nrnr transitions, which result from the fact that the mesophase directors are aligned homogeneously by the magnetic field of the spectrometer (1 3).Of particular utility in the study of ion binding is the mixed detergent system prepared from potassium dodecanoate (potassium laurate) and alkyltrimethylammonium bromide. This system has the advantage in that, under the appropriate conditions, the potassium dodecanoate can be replaced in a stepwise fashion by alkyltrimethylammonium bromide, thus progressing

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“…In a first approximation this displacement may be assumed to be linear so that eq. [6] is obtained from eq. [4].…”

Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The interactions of the chloride and bromide ions in nematic lyotropic liquid crystalline solution

Tracey¹

1984

Can. J. Chem.

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“…The de novo design of peptides that fold into well-defined secondary and tertiary structures provides a biological construct in which one can engineer metal-binding sites and assess the factors controlling structure and site specificity. Currently efforts in our research laboratory are directed toward trying to achieve a similar degree of control, in particular for binding Cd(II) in biologically common thiol-rich sites, because Cd(II) is frequently substituted as a probe for Zn(II) (7,8). A key benefit of the direct chemical synthesis of these constructs is that we are no longer limited to the 20 naturally occurring amino acids and can take full advantage of the extensive library of nonnatural amino acids.…”

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confidence: 99%

Using diastereopeptides to control metal ion coordination in proteins

Peacock

Hemmingsen

Pecoraro

2008

Proc. Natl. Acad. Sci. U.S.A.

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Here, we report a previously undescribed approach for controlling metal ion coordination geometry in biomolecules by reorientating amino acid side chains through substitution of L-to D-amino acids. These diastereopeptides allow us to manipulate the spatial orientation of amino acid side chains to alter the sterics of metal binding pockets. We have used this approach to design the de novo metallopeptide, Cd (TRIL12L DL16C)

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“…Despite the considerable literature concerning n3Cd NMR spectra of coordination compounds and proteins (e.g., Armitage et aL, 1976;Summers, 1988), relatively few studies used NMR methods to probe the interaction between Cd and swelling phyllosilicates. Nevertheless NMR was used to study ll3Cd sorbed on montmorillonite by Bank et al (1989).…”

Section: Introductionmentioning

confidence: 99%

Nuclear Magnetic Resonance (NMR) Study of Cd²⁺ Sorption on Montmorillonite

Leo¹,

O’Brien

1999

Clays and clay miner.

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Abstrac~z13Cd solid-state nuclear magnetic resonance (NMR) was used to identify possible Cd 2+ adsorption sites in montmorillonite. The montmorillonite was treated with 0.1 and 1 M CdC12 aqueous solutions and samples with 13 and 8-txm particle size were used. The data are consistent with a two-site model for sorption of Cd 2+ on montmorillonite. Cd 2+ is localized in the montmorillonite in two different sites: 1) in the interlayers as hydrated Cd z+ and 2) on the external surface, probably with few H20 molecules hydrating to it. Cadmium is also adsorbed as CdC1 + in the interlayer. Treatment with a 0.1 M CdClz solution produces adsorption of free Cd 2+ in the interlayer whereas treatment with 1 M CdCI2 resulted in adsorption of Cd 2+ in both the interlayer and on surface sites and the adsorption of CdC1 + in the interlayer. A larger particle size favors Cd z+ adsorption on the external surface whereas a smaller particle size favors Cd 2+ adsorption in the interlayer.

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Cadmium-113 Fourier transform nuclear magnetic resonance of cadmium(II) carbonic anhydrases and cadmium(II) alkaline phosphatase

Cited by 79 publications

References 5 publications

The interactions of the chloride and bromide ions in nematic lyotropic liquid crystalline solution

The interactions of the chloride and bromide ions in nematic lyotropic liquid crystalline solution

Using diastereopeptides to control metal ion coordination in proteins

Nuclear Magnetic Resonance (NMR) Study of Cd²⁺ Sorption on Montmorillonite

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Cadmium-113 Fourier transform nuclear magnetic resonance of cadmium(II) carbonic anhydrases and cadmium(II) alkaline phosphatase

Cited by 79 publications

References 5 publications

The interactions of the chloride and bromide ions in nematic lyotropic liquid crystalline solution

The interactions of the chloride and bromide ions in nematic lyotropic liquid crystalline solution

Using diastereopeptides to control metal ion coordination in proteins

Nuclear Magnetic Resonance (NMR) Study of Cd2+ Sorption on Montmorillonite

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Product

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Nuclear Magnetic Resonance (NMR) Study of Cd²⁺ Sorption on Montmorillonite