Cadmium, Cd

Tomza–Marciniak, Agnieszka; Pilarczyk, Bogumiła; Marciniak, Andrzej; Udała, J.; Bąkowska, Małgorzata; Pilarczyk, Renata

doi:10.1007/978-3-030-00121-6_14

Cited by 11 publications

(4 citation statements)

References 181 publications

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“…Similar to the macroinvertebrates, wood mice collected from contaminated sites accumulated significantly more Pb and Cd than wood mice from the control sites, as has been observed in previous studies [ [57] , [58] , [59] , [60] , [61] ]. While other factors, such as location, season, and age, affected non-essential metal exposure, as expected [ 58 , 60 , [62] , [63] , [64] ], the concentrations of non-essential trace metals in the environment did have an effect on trace metal tissue concentrations in wood mice.…”

Section: Discussionsupporting

confidence: 61%

“…This agrees with prior studies on wood mice in Cd-polluted sites, which have found elevated kidney and liver Cd concentrations, but little Cd accumulation in bones [ 57 , 59 ]. While most studies in contaminated sites have reported rodent Cd tissue concentrations higher than those observed in the current study [ 38 , 59 , 61 , 64 , 73 ], this finding was expected, as mine sites in western Wales are known to have relatively low soil Cd concentrations [ 63 ]. As such, the wood mouse Cd concentrations observed during this study were uniformly below Shore & Douben's [ 39 ] proposed threshold for kidney damage in small mammals of 105 mg kg −1 d.w.…”

Section: Discussionsupporting

confidence: 51%

See 1 more Smart Citation

Trace metal accumulation through the environment and wildlife at two derelict lead mines in Wales

Sartorius,

Johnson,

Young

et al. 2024

Heliyon

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Section: Discussionsupporting

confidence: 61%

Section: Discussionsupporting

confidence: 51%

Trace metal accumulation through the environment and wildlife at two derelict lead mines in Wales

Sartorius,

Johnson,

Young

et al. 2024

Heliyon

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“…It is predominantly expelled from the body through the kidneys in urine, with prolonged exposure potentially impairing renal function and reducing excretory efficiency. With a biological half-life of 10 to 30 years, Cd can accumulate in the body for decades after absorption [ 1 , 12 ]. This prolonged accumulation means that even low-dose exposure also can ultimately lead to severe health damage.…”

Section: The Absorption Distribution Metabolism and Excretion (Adme) ...mentioning

confidence: 99%

Cadmium Exposure: Mechanisms and Pathways of Toxicity and Implications for Human Health

Qu,

Zheng

2024

Toxics

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Cadmium (Cd), a prevalent environmental contaminant, exerts widespread toxic effects on human health through various biochemical and molecular mechanisms. This review encapsulates the primary pathways through which Cd inflicts damage, including oxidative stress induction, disruption of Ca2+ signaling, interference with cellular signaling pathways, and epigenetic modifications. By detailing the absorption, distribution, metabolism, and excretion (ADME) of Cd, alongside its interactions with cellular components such as mitochondria and DNA, this paper highlights the extensive damage caused by Cd2+ at the cellular and tissue levels. The role of Cd in inducing oxidative stress—a pivotal mechanism behind its toxicity—is discussed with emphasis on how it disrupts the balance between oxidants and antioxidants, leading to cellular damage and apoptosis. Additionally, the review covers Cd’s impact on signaling pathways like Mitogen-Activated Protein Kinase (MAPK), Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-κB), and Tumor Protein 53 (p53) pathways, illustrating how its interference with these pathways contributes to pathological conditions and carcinogenesis. The epigenetic effects of Cd, including DNA methylation and histone modifications, are also explored to explain its long-term impact on gene expression and disease manifestation. This comprehensive analysis not only elucidates the mechanisms of Cd toxicity but also underscores the critical need for enhanced strategies to mitigate its public health implications.

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“…Cadmium (Cd) considered the third most dangerous metal in the environment after mercury and lead and the concentrations of Cd that are not toxic to plant are hazardous to both of human and animals (Ismael et al, 2019;Tomza-Marciniak et al, 2019). It reaches the soil, water and plants through anthropogenic activities, it is accessible for plant absorption since it is more soluble than the other heavy metals, and its uptake process by plants through the soil is enhanced while the pH is acidic (Järup, 2003), those gathered in different plant parts (Farid et al, 2015).…”

Section: Concentration Of Cu and CD In Roots And Shootsmentioning

confidence: 99%

GROWTH RESPONSE OF Eucalyptus Camaldulensis DHENH. AND Melia Azedarach L. SEEDLINGS TO PRIMARY TREATED WASTEWATER OF AVROCITY IN DUHOK GOVERNORATE

AHMED

2019

juod

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An experiment was conducted during April to the beginning of November ,2018, in the lath house of the University of Duhok, College of Agricultural Engineering Sciences, Duhok city. This research was carried out to study the effect of primary treated wastewater (PTWW) of Avro city in Duhok governorate ,Iraq, on Eucalyptus camaldulensis and Melia azedarach one-and two-years old seedlings, and some growth parameters (seedlings biomass, diameter and height) were investigated at the beginning and at the end of the study, the total chlorophyll content measured, ,concentration of (Cd and Cu) and some chemical and physical properties of soil and water were determined. Chlorophyll content show significant effect for PTWW applied on Melia seedlings for both ages and the highest value was 49.90 (SPAD) in Melia seedling of one year irrigated with PTWW. Irrigation with PTWW increased significantly the growth parameters (seedlings height, diameter, and biomass) in Melia. The obtained results show that PTWW effects on the biomass of 1-year old Melia seedlings followed by 2-years old Melia seedlings, while for Eucalyptus, comparable results shown for the 2-years old seedling treated with the both types of water, while for the smaller seedlings (in age) the tap water (TW) was more effective. Concerning the heavy metals, surprisingly, Cu was higher in plants parts irrigated with TW compared with that of PTWW. The highest Cu concentration found in the roots of 2-years old Melia seedlings (23.93 mg.kg-1 d.wt), with the lowest concentration in 1-year old Eucalyptus seedlings (12.02 mg.kg-1 d.wt). In general, highest Cd concentration detected in roots and shoots treated with PTWW, whereas the uppermost (mean) Cd concentration was found in two-years old roots of Eucalyptus seedlings (1.16 mg.kg-1 d.wt) besides the lowest results noted in two-years old shoots of Melia seedlings that stands on (0.20 mg.kg-1 d.wt). As a result, Melia was more resistance to PTWW than Eucalyptus.

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Cadmium, Cd

Cited by 11 publications

References 181 publications

Trace metal accumulation through the environment and wildlife at two derelict lead mines in Wales

Trace metal accumulation through the environment and wildlife at two derelict lead mines in Wales

Cadmium Exposure: Mechanisms and Pathways of Toxicity and Implications for Human Health

GROWTH RESPONSE OF Eucalyptus Camaldulensis DHENH. AND Melia Azedarach L. SEEDLINGS TO PRIMARY TREATED WASTEWATER OF AVROCITY IN DUHOK GOVERNORATE

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