Cadmium exposure and its health effects: A 19-year follow-up study of a polluted area in China

Zhang, Wenli; Du, Yu; Zhai, Miao-Miao; Shang, Qi

doi:10.1016/j.scitotenv.2013.09.070

Cited by 183 publications

(58 citation statements)

References 15 publications

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“…The concentration of Cd in rice from polluted areas in Jiangxi Province of China in 2006 was nearly 3 times higher than the Chinese Hygienic Standard for rice (Zhang, Du, Zhai, & Shang, 2014). Another study conducted in a heavy metal polluted village in Vietnam in 2007 showed that the Cd concentration of rice in that area was 0.31 mg/kg, significantly higher than the allowable Cd level in rice (0.20 mg/kg), as published by the Vietnamese Ministry of Health (Minh et al, 2012).…”

Section: Discussionmentioning

confidence: 91%

Screening of lactic acid bacteria with potential protective effects against cadmium toxicity

et al. 2015

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Section: Discussionmentioning

confidence: 91%

Screening of lactic acid bacteria with potential protective effects against cadmium toxicity

et al. 2015

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“…Workers of a large variety of occupations, especially those are involved in manufacture of alloy and battery, and nonferrous metal smelting and refining, are exposed to high level of cadmium through inhalation of dust and fumes, and incidental ingestion of dust from contaminated hands, cigarettes or foods. The rapid economic growth in China during the past three decades has led to the increased consumption of cadmium related products and the expansion of occupational cadmium exposed population [24]. Cadmium exposure of general population in China and other Asian countries is generally higher than in Europe and the United States, because of the large number of cadmium-polluting industries and high intake of rice and vegetables grown locally in cadmium-contaminated soil [25,26].…”

Section: Discussionmentioning

confidence: 99%

Cadmium Exposure is Associated with the Prevalence of Dyslipidemia

Zhou¹,

Lu²,

Pi³

et al. 2016

Cell Physiol Biochem

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Background: Cadmium is a widespread environmental and occupational pollutant that accumulates in human body with a biological half-life exceeding 10 years. Cadmium exposure has been demonstrated to increase rates of cardiovascular diseases. Whether occupational cadmium exposure is associated with the increase in the prevalence of dyslipidemia and hence contributes to the risk of cardiovascular diseases is still equivocal. To test the hypothesis that exposure to cadmium is related to the prevalence of dyslipidemia, we examined the associations between blood cadmium concentration and the prevalence of dyslipidemia in workers occupationally exposed to cadmium in China. Methods: A cross-sectional survey on demographic data, blood cadmium level and lipid profile in cadmium exposed workers from seven cadmium smelting factories in central and southwestern China was conducted. We measured blood cadmium concentration and lipid components of 1489 cadmium exposed workers. The prevalence of dyslipidemia was compared across blood cadmium quartiles. Associations between the blood cadmium concentrations and the prevalence of dyslipidemia were assessed using confounder adjusted linear and logistic regressions. Results: The blood cadmium concentration was 3.61±0.84µg/L ( mean ±SD). The prevalence of dyslipidemia in this occupational population was 66.3%. Mean blood cadmium concentration of workers with dyslipedemia was significantly higher than that of workers without dyslipidemia (p <0.01). The prevalence of dyslipidemia increased dose-dependently with elevations in blood cadmium concentrations (p for trend <0.001). Elevated levels of blood cadmium were associated with BMI, education attainment, income, smoking status and duration of exposure (all p <0.01). Furthermore, the profile of blood lipid was obviously changed in this occupational population. The prevalence of high TC, high TG, Low HDL-C and high LDL-C rose with increases in blood cadmium levels dose-dependently (p for trend <0.001). The odds ratios (95% confidence interval) for dyslipidemia across the increasing blood cadmium quartiles were 1.21(1.16-1.55), 1.56(1.11-1.87), 1.79(1.26-2.25) respectively (referencing to 1.00; p for trend <0.001), after multivariate adjustment for BMI, education attainment, income, lifestyle factors and duration of exposure, the association between blood cadmium concentrations and the prevalence of dyslipidemia remained unchanged (all p for trend <0.001). Conclusion: Elevated blood cadmium concentration is associated with prevalence of dyslipidemia. Cadmium exposure could alter lipid metabolism in humans. It is imperative to control cadmium exposure of occupational population in cadmium related industries and reduce adverse health effects.

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“…Since the appearance of the Itai-Itai disease in Japan in 1912, the environmental impact of Cd has been the object of significant societal concern. Numerous studies have reported Cd contamination of soils, food crops, water and sediments worldwide, leading to serious potential health risks to humans (e.g., Robson et al, 2014;Zhang et al, 2014). Cadmium in soils may transfer to crops with a high soil-to-plant transfer factor, as a result of the influence of soil characteristics (pH, SOM, etc.…”

Section: Introductionmentioning

confidence: 99%

Potential health risk in areas with high naturally-occurring cadmium background in southwestern China

Liu

Xiao

Baveye

et al. 2015

Ecotoxicology and Environmental Safety

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Cadmium exposure and its health effects: A 19-year follow-up study of a polluted area in China

Cited by 183 publications

References 15 publications

Screening of lactic acid bacteria with potential protective effects against cadmium toxicity

Screening of lactic acid bacteria with potential protective effects against cadmium toxicity

Cadmium Exposure is Associated with the Prevalence of Dyslipidemia

Potential health risk in areas with high naturally-occurring cadmium background in southwestern China

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