Caffeine as a contaminant of concern: A review on concentrations and impacts in marine coastal systems

Vieira, Luís R.; Soares, Amadeu M.V.M.; Freitas, Rosa

doi:10.1016/j.chemosphere.2021.131675

Cited by 63 publications

(38 citation statements)

References 101 publications

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“…Usually, deleterious effects of pollutants are conditioned to their environmental concentrations, toxicity and mechanisms of action (Halling-Sørensen et al 1998;Fent et al 2006). Despite the higher biodegradation facility of caffeine, recent studies showed deleterious effects on aquatic organisms (Vieira et al 2022;Wilkinson et al 2022), such as oxidative balance in fishes (Santos-Silva et al 2018), inducing an increase in plasma vitellogenin in male individuals of Carassius auratus exposed to a few days of lower concentrations (Li et al 2012), up to extreme skeletal deformations and reduced growth in exposed larvae of an endemic neotropical catfish (Rhamdia quelen) (Santos et al 2022). Therefore, caffeine may be a strong agent of estrogenicity in aquatic organisms (Montagner et al 2014), suggesting caution in evaluating caffeine in monitored streams and further studying the effects on native fauna (Santos-Silva et al 2018;Godoi et al 2020) and human populations.…”

Section: Rq For Target Pacmentioning

confidence: 99%

“…The PAC arouse concern by represent one major category of anthropogenic contaminants present in the aquatic environment, with high global consumption and a representative incidence in surface and groundwater samples, degrading water quality, as documented in several publications (Zhou et al 2019;Richardson and Kimura 2020;Liu et al 2020;Vieira et al 2022;Wilkinson et al 2022).…”

Section: Introductionmentioning

confidence: 99%

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Presence and risk assessment of pharmaceutically active compounds in neotropical small basins, Brazil

Minillo

Isique

Cardoso

et al. 2022

Preprint

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Pharmaceutically active compounds (PAC) are micropollutants that represent emerging contaminants (ECs) commonly found in aquatic environments. Exposure of aquatic biota to these identified ECs has resulted in severe effects. In the last few years, the number of studies on PAC has grown quickly owing to increasing awareness of the potential environmental and health risks related to these micropollutants. The aim of our study was to evaluate the contamination levels of selected PAC and their potential ecological threat to forested streams. Samples of stream water were collected in the second largest city in Mato Grosso do Sul State in center-west of Brazil. Physicochemical parameters and concentrations of PAC were quantified in samples collected in six field campaigns. Ecological risk assessment (ERA) based on risk quotient (RQ) was carried out based on the maximum measured concentration of PAC in water. Six pharmaceutical compounds were successfully quantified in the forested streams, namely caffeine (1.0 – 1,696.04 ng/L), naproxen (0.9 – 681.80 ng/L), diclofenac (0.8 – 849.94 ng/L), estriol (0.9 – 13.22 ng/L), estradiol (0.9 – 587.30 ng/L) and ethinylestradiol (0.9 – 790.90 ng/L). From an ecological risk perspective, ethinylestradiol, estradiol, diclofenac and caffeine can be considered as priority PAC because they showed moderate to high risks to aquatic organisms and may further lead to damages along the food chain. This study provides valuable information to reinforce the importance of continuous monitoring of the forested streams in center-west region of the country, as well as efforts to control the entry of these micropollutants in watercourse.

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Section: Rq For Target Pacmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Presence and risk assessment of pharmaceutically active compounds in neotropical small basins, Brazil

Minillo

Isique

Cardoso

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…Increasing evidences suggest that caffeine concentrations exert adverse impacts on aquatic and terrestrial species (11,12). For example, several studies reported the distribution of caffeine in tissues of aquatic organisms including macroalgae, fishes, clams, and other aquatic plants after being grown in the caffeine-contaminated environment (11)(12)(13)(14)(15)(16). Studies have also reported caffeine accumulation in the coastal ecosystems, raising concerns about its potential impacts on the ecological safety (12)(13)(14)(15)(16).…”

Section: Introductionmentioning

confidence: 99%

Urate oxidase from tea microbe Colletotrichum camelliae is involved in the caffeine metabolism pathway and plays a role in fungal virulence

Qiao

Zhang

et al. 2023

Front. Nutr.

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Tea is one of the most well-known, healthy beverages in the world. Tea plants produce caffeine as a secondary metabolite. Colletotrichum camelliae is one of the most important microbes frequently isolated from tea fields, and it causes anthracnose disease in tea plant. In the present work, we performed molecular microbiology and transcriptomic analyses of the C. camelliae - tea plant interaction to investigate the mechanism of fungal virulence and plant defense. Upon infection of tea plant with C. camelliae, we observed alterations in the expression of fungal transcripts, including those of many genes associated with caffeine metabolism, such as those encoding various transporters, xanthine dehydrogenase, and urate oxidase (UOX). In particular, the deletion of C. camelliae urate oxidase (CcUOX), which is involved in the caffeine metabolism pathway, reduced fungal tolerance to caffeine, and impaired fungal virulence. CcUOX is involved in caffeine metabolism by the degradation of uric acid contents. C. camelliaeΔCcUOX mutants impaired uric acid degradation in vivo. The CcUOX gene was cloned from C. camelliae, overexpressed in Escherichia coli, and the recombinant CcUOX protein displayed maximum activity at 30°C and a pH of 4.0. The recombinant CcUOX efficiently reduced uric acid in vitro suggesting a promising application in caffeine-contaminated environment management and in producing food with low purine contents to prevent uric acid related human diseases, such as hyperuricemia and gout.

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“…The large-scale disposal of this biowaste in landfills could endanger human and environmental health since its extractives are reported to induce mutagenic and genotoxic effects, while caffeine (0.07-0.5 wt% of SCG) could cause adverse effects on aquatic organisms and ecosystem functioning. [27,28] Fortunately, in addition to being a sugar-rich lignocellulosic source, SCG has compelling features of water and oil holding capacity, thermostability, antioxidant potential, and so forth. Therefore, its versatility has been valorized as substrates assisting fungal growth in fermentation, adsorbents employed for the removal of odoriferous compounds (deodorization) and heavy metals from wastewater, bioreinforcing agents in polymer composites, and so forth.…”

Section: Introductionmentioning

confidence: 99%

Spent coffee grounds: An intriguing biowaste reinforcement of thermoplastic starch with potential application in green packaging

et al. 2022

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With respect to the explosion of single-use plastic packaging consumption during the COVID-19 pandemic, environmentally friendly substitutes are critically needful for sustainable development. Therefore, the present work focuses on the functional properties of bioplastic blends prepared through hot compressing molding of thermoplastic starch (TPS) and spent coffee grounds (SCG) in different ratios (0%-20% SCG) as the potential features of SCG were extensively employed in biocomposites for the first time. The insertion of dark brown SCG into TPS hindered UV transmission by 100% at 320 nm and 99.2% at 400 nm. Moreover, the samples with 15% and 20% SCG induced a surge in radical scavenging activity from 7.95% to over 92% at a concentration of 0.1 g/ml owing to the rich source of antioxidants in SCG. The lignin component and high carbon content also improved the thermal performance of TPS/SCG blends, enhancing thermal stability, delaying onset and maximum degradation temperatures, and achieving the HB rating in the UL-94 test. Compared to a pure TPS matrix, TPS blends incorporating up to 10% SCG exhibited improvement in elastic modulus without deterioration of tensile strength.

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Caffeine as a contaminant of concern: A review on concentrations and impacts in marine coastal systems

Cited by 63 publications

References 101 publications

Presence and risk assessment of pharmaceutically active compounds in neotropical small basins, Brazil

Presence and risk assessment of pharmaceutically active compounds in neotropical small basins, Brazil

Urate oxidase from tea microbe Colletotrichum camelliae is involved in the caffeine metabolism pathway and plays a role in fungal virulence

Spent coffee grounds: An intriguing biowaste reinforcement of thermoplastic starch with potential application in green packaging

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