We prove the mean curvature flow of a spacelike graph in ( 1 × 2 , g 1 − g 2 ) of a map f : 1 → 2 from a closed Riemannian manifold ( 1 , g 1 ) with Ricci 1 > 0 to a complete Riemannian manifold ( 2 , g 2 ) with bounded curvature tensor and derivatives, and with sectional curvatures satisfying K 2 ≤ K 1 , remains a spacelike graph, exists for all time, and converges to a slice at infinity. We also show, with no need of the assumption K 2 ≤ K 1 , that if K 1 > 0, or if Ricci 1 > 0 and K 2 ≤ −c, c > 0 constant, any map f : 1 → 2 is trivially homotopic provided f * g 2 < ρg 1 where ρ = min 1 K 1 / sup 2 K + 2 ≥ 0, in case K 1 > 0, and ρ = +∞ in case K 2 ≤ 0. This largely extends some known results for K i constant and 2 compact, obtained using the Riemannian structure of 1 × 2 , and also shows how regularity theory on the mean curvature flow is simpler and more natural in pseudo-Riemannian setting then in the Riemannian one.