Calcified structures associated with human skeletal remains: Possible atherosclerosis affecting the population buried at Amara West, Sudan (1300–800BC)

Binder, Michaela; Roberts, Charlotte A.

doi:10.1016/j.ijpp.2014.03.003

Cited by 36 publications

(11 citation statements)

References 43 publications

(41 reference statements)

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“…In archeological skeletons, the prevalence of IPR on ribs may offer useful insight into the presence of, and exposure to, lower respiratory tract diseases, as well as provide information about poor air quality from many causes. For example, cramped and badly ventilated living quarters and exposure to particulate pollution such as dust, sand, pollen, cooking fires, and habitual smoking have all been discussed as causative factors in relation to the presence of IPR in different archeological settings, and high population density also predisposes to the ready transmission of lower respiratory tract diseases (Binder, , pp. 303–305; Capasso, ; Lambert, ; Pfeiffer, ; Roberts, ; Walker & Henderson, ).…”

Section: Introductionmentioning

confidence: 99%

Inflammatory periosteal reaction on ribs associated with lower respiratory tract disease: A method for recording prevalence from sites with differing preservation

Davies-Barrett

Antoine

Roberts

2019

American J Phys Anthropol

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Objectives Inflammatory periosteal reaction (IPR) on the visceral surfaces of the ribs has been used in bioarchaeology as an indicator of lower respiratory tract disease. This article presents a detailed method for recording IPR on the ribs, even those in severely fragmented states, with the objectives of increasing the consistency of recording and producing true prevalence rates for skeletons so as to improve data comparability between future bioarchaeological studies of lower respiratory tract disease. Materials and methods The presence and prevalence of respiratory‐related IPR were recorded from three different Sudanese cemetery sites using a detailed method for identifying and recording IPR. Sites with variable preservation were chosen to test the applicability of the method. A flowchart to aid in identification of bony changes is presented. The method requires the recording of IPR on three separate sections of the rib (neck, angle, and shaft) and the allocation of ribs into rib cage regions of upper, upper‐middle, middle, lower‐middle, and lower. Results Results demonstrate differences in the distribution of IPR between sites and verify the method's applicability to archeological sites with various levels of skeletal preservation. Discussion While crude prevalence rates can indicate the number of individuals experiencing lower respiratory tract disease within a site, this method can provide information about the distribution of IPR within the rib cage. This should lead to new ways of distinguishing respiratory diseases within archeological populations. This method also allows for comparability between well‐preserved and lesser‐preserved sites by accommodating for rib fragmentation.

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Section: Introductionmentioning

confidence: 99%

Inflammatory periosteal reaction on ribs associated with lower respiratory tract disease: A method for recording prevalence from sites with differing preservation

Davies-Barrett

Antoine

Roberts

2019

American J Phys Anthropol

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“…Plaques of atherosclerosis are occasionally preserved (Binder & Roberts 2014;Subirana-Domènech et al 2012;Thompson et. al.…”

Section: Coronary Heart Disease/chd Nomentioning

confidence: 99%

“…2013). CHD is indicated where atherosclerosis affects coronary arteries Currently unclear (Binder & Roberts 2014;Thompson et al 2013). Exposure to environmental pollutants such as wood-smoke increases risk (Fullerton et al 2008), as may lack of physical activity, smoking, obesity and dietary factors (WHO & UNAIDS 2007)…”

Section: Coronary Heart Disease/chd Nomentioning

confidence: 99%

Ageing and the Body in Archaeology

Appleby

2017

CAJ

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“…Like autoimmune disorders, cancer and cardiovascular disease are rarely visible within the bioarchaeological record and this is likely because the majority of these conditions do not directly affect bone and often rapidly result in death without medical intervention. However, they are major causes of morbidity and mortality in contemporary populations (World Health Organization, , b) and there is some evidence for metastatic cancer and arteriosclerosis in the bioarchaeological record (Manchester, ; Zimmerman, ; Luna et al, ; Domett and Buckley, ; Binder and Roberts, ). Therefore, consideration of the association between poor vitamin D status and increased risk for these conditions is needed when considering the epidemiological impact of vitamin D insufficiency in the past.…”

Section: “Novel” Roles Of Vitamin D Hormone In Human Physiologymentioning

confidence: 99%

More than metabolic: Considering the broader paleoepidemiological impact of vitamin D deficiency in bioarchaeology

Snoddy

Buckley

Halcrow

2016

American J Phys Anthropol

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Vitamin D deficiency has traditionally been viewed as a metabolic bone disease by bioarchaeologists and considered primarily in terms of the development of specific musculoskeletal changes used for diagnosis in paleopathological research. These skeletal manifestations are usually interpreted as representing general ill-health. Clinical research shows that vitamin D is also integral to a number of extra-skeletal physiological processes including immunoregulation, blood pressure homeostasis, cell division, and programmed cell death. Vitamin D deficiency and sub-clinical insufficiency are thought to be risk factors for infectious and autoimmune diseases, as well as certain cancers and cardiovascular diseases. Epidemiological work indicates that the skeletal manifestations of vitamin D deficiency represent the extreme end of a spectrum of morbidity associated with negative health outcomes, including increased risk for secondary tuberculosis. This article provides a review of clinical research on the extra-skeletal roles of vitamin D and the pathological consequences of poor vitamin D status. Additionally, it presents an interpretive model for bioarchaeological analyses of rickets and osteomalacia for consideration of the whole-body impact of poor vitamin D nutriture and possible comorbidities that may have affected the wider population. Am J Phys Anthropol 160:183-196, 2016. © 2016 Wiley Periodicals, Inc.

show abstract

Calcified structures associated with human skeletal remains: Possible atherosclerosis affecting the population buried at Amara West, Sudan (1300–800BC)

Cited by 36 publications

References 43 publications

Inflammatory periosteal reaction on ribs associated with lower respiratory tract disease: A method for recording prevalence from sites with differing preservation

Inflammatory periosteal reaction on ribs associated with lower respiratory tract disease: A method for recording prevalence from sites with differing preservation

Ageing and the Body in Archaeology

More than metabolic: Considering the broader paleoepidemiological impact of vitamin D deficiency in bioarchaeology

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