Calciphylaxis associated with rheumatoid arthritis: communication of the second case

Abstract

Calciphylaxis is the tissue sensitivity to calcification, described mainly in patients with chronic renal insufficiency, renal transplant of parathyroid dysfunction. There is only one case described in a patient with rheumatoid arthritis, without renal dysfunction, nor hyperparathyroidism. We present the second case in a woman with inactive rheumatoid arthritis.

Clinical Significance of Trochlear Calcifications in the Orbit

“…13,14 The deposition of calcification can be idiopathic, dystrophic, or due to calciphylaxis, and while the pathophysiology is unclear, it is thought to relate to circulating chronic inflammatory mediators. [15][16][17][18][19][20][21][22][23][24][25][26][27] Case reports describe both focal and extensive systemic deposition of calcification in patients with both rheumatoid arthritis and SLE, with calciphylaxis described as a rare complication of both diseases. [16][17][18][19][20][21][22][23] SLE can lead to CKD, a well-known complication 22 ; however, CKD was not independently associated with trochlear calcifications.…”

“…Widespread soft-tissue calcification in chronic inflammatory autoimmune disorders such as Sjögren syndrome, SLE, and rheumatoid arthritis has been described. [20][21][22][23][25][26][27] Very few case reports describe focal calcifications within the soft tissues of the head and neck, with the exception of retropharyngeal calcific tendinitis and calcification of the longus colli muscle in a patient with rheumatoid arthritis. 28 On the basis of the results of this investigation, it appears that in addition to calcification within soft tissues previously described, trochlear calcifications may also be seen as an associated finding in patients with autoimmune conditions.…”

Calciphylaxis of the temporal artery masquerading as temporal arteritis: a case presentation and review of the literature

“…Nigwekar et al [1] published a review of non-uremic causes of calciphylaxis and described its association with alcoholic liver disease, diabetes, vitamin D deficiency, Crohn disease, POEMS syndrome, rheumatoid arthritis [4], and GCA among other pathologies; none of which were found in the patient described here.…”

“…), many cases are due to non-uremic causes [1,4]. This condition is characterized by ecchymotic or infarcted symmetrical areas, mainly in the lower limbs [3].…”

Calciphylaxis Associated With Rheumatoid Arthritis: Communication of Another Case

“…[2][3][4][5] The data on its association with rheumatoid arthritis in the absence of renal failure and hyperparathyroidism are limited. 1,[6][7][8][9] ଝ Please cite this article as: Ortiz Objective: To report a case of calciphylaxis in a patient with inactive rheumatoid arthritis without renal failure or hyperparathyroidism.…”